(-)-Epigallocatechin Gallate (ab120716)
- Product name(-)-Epigallocatechin Gallate
- DescriptionPotent anti-oxidant flavonoid
- Biological descriptionPotent anti-oxidant flavonoid. Displays anti-cancer, anti-tumour activity and induces apoptosis. Modulates numerous cell signalling pathways, such as inhibiting NF-κB, MAPK and COX-2 pathways. Also shows anti-inflammatory, anti-bacterial and anti-viral activities (EC50 = ~22 for inhibition of influenza virus).
- Purity> 98%
- Chemical name(−)-cis-3,3′,4′,5,5′,7-Hexahydroxyflavane-3-gallate
- Molecular Weight458.38
- Chemical structure
- Molecular formulaC22H18O11
- CAS Number989-51-5
- Storage instructionsStore at +4°C (desiccating conditions).
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
- Pathways and Processes
- Metabolic signaling pathways
- Lipid and lipoprotein metabolism
- Cholesterol Metabolism
References for (-)-Epigallocatechin Gallate (ab120716)
This product has been referenced in:
- Khan N et al. Targeting multiple signaling pathways by green tea polyphenol (-)-epigallocatechin-3-gallate. Cancer Res 66:2500-5 (2006). Read more (PubMed: 16510563) »
- Williamson MP et al. Epigallocatechin gallate, the main polyphenol in green tea, binds to the T-cell receptor, CD4: Potential for HIV-1 therapy. J Allergy Clin Immunol 118:1369-74 (2006). Read more (PubMed: 17157668) »
- Song JM et al. Antiviral effect of catechins in green tea on influenza virus. Antiviral Res 68:66-74 (2005). Read more (PubMed: 16137775) »