Overview

  • Product nameAnti-14-3-3 Tau antibodySee all 14-3-3 Tau primary antibodies ...
  • Description
    Rabbit polyclonal to 14-3-3 Tau
  • SpecificityThis antibody recognises 14-3-3 tau. It may not react with recombinant proteins that are not N-acetylated.
  • Tested applicationsWB, ELISA, IHC-Pmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Sheep, Chicken, Cow, Human
  • Immunogen

    Synthetic peptide corresponding to acetylated N terminal sequence (Sheep) of 14-3-3 Tau

  • Positive control
    • IHC-P: Normal tonsil tissue. WB: HEK293 cell lysates.

Properties

Applications

Our Abpromise guarantee covers the use of ab53200 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB
ELISA
IHC-P
  • Application notesELISA: Use at an assay dependent dilution.
    IHC-P: Use at an assay dependent dilution.
    WB: Use at an assay dependent dilution. Detects a band of approximately 30 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    Supplied as a serum, the conc will be approximately 0.5 -1mg/ml specific antibody

    We do not have specific dilutions for this antibody and we always suggest that the user titrates the antibody in their own system. However the following RWD would be a good starting point, IHC-p 10ug/ml, ELISA 1-10ug/ml, WB 1-10ug/ml.

  • Target

    • FunctionAdapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.
    • Tissue specificityAbundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement.
    • Sequence similaritiesBelongs to the 14-3-3 family.
    • Post-translational
      modifications
      Ser-232 is probably phosphorylated by CK1.
    • Cellular localizationCytoplasm. In neurons, axonally transported to the nerve terminals.
    • Information by UniProt
    • Database links
    • Alternative names
      • 14 3 3 protein T cell antibody
      • 14 3 3 protein tau antibody
      • 14 3 3 protein theta antibody
      • 14 3 3 tau antibody
      • 14 3 3 theta antibody
      • 14-3-3 protein T-cell antibody
      • 14-3-3 protein tau antibody
      • 14-3-3 protein theta antibody
      • 1433T_HUMAN antibody
      • 1C5 antibody
      • HS1 antibody
      • KCIP1 antibody
      • Protein HS1 antibody
      • Protein kinase C inhibitor protein 1 antibody
      • Protein tau antibody
      • tyr3/trp5 monooxygenase activation protein, theta antibody
      • Tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, theta polypeptide antibody
      • YWHAQ antibody
      see all

    References for Anti-14-3-3 Tau antibody (ab53200)

    ab53200 has not yet been referenced specifically in any publications.

    Product Wall

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"