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Overview

  • Product name14-3-3 beta protein (Human)See all 14-3-3 beta proteins and peptides ...
  • Protein descriptionRecombinant full length human 14-3-3 beta; 246 amino acids, 28kDa. Swiss ID = P31946.
  • Expression hostE. coli

    • Properties

  • Purity> 90 % by SDS-PAGE
  • Purification notesab78683 is purified using conventional chromatography techniques.
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 50mM Sodium chloride, 20mM Tris, 1mM EDTA, pH 8.0
  • Concentration information loading...
  • Sequence notesMTMDKSELVQ KAKLAEQAER YDDMAAAMKA VTEQGHELSN EERNLLSVAY KNVVGARRSS WRVISSIEQK TERNEKKQQM GKEYREKIEA ELQDICNDVL ELLDKYLIPN ATQPESKVFY LKMKGDYFRY LSEVASGDNK QTTVSNSQQA YQEAFEISKK EMQPTHPIRL GLALNFSVFY YEILNSPEKA CSLAKTAFDE AIAELDTLNE ESYKDSTLIM QLLRDNLTLW TSENQGDEGD AGEGEN
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab78683 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab6081.

    • Protein info

    • Alternative names
        14 3 3 protein beta/alpha14-3-3 protein beta/alpha1433B_HUMAN
        Brain protein 14 3 3 beta isoformGW 128GW128HS 1HS1KCIP 1KCIP-1KCIP1N-terminally processedProtein 1054Protein kinase C inhibitor protein 1Tyrosine 3 Monooxygenase/Tryptophan 5 Monooxygenase Activation Protein Beta PolypeptideYWHAAYWHAB
      see all
  • FunctionAdapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis.
  • Sequence similaritiesBelongs to the 14-3-3 family.
  • Post-translational
    modifications    The alpha, brain-specific form differs from the beta form in being phosphorylated.
    Isoform Short contains a N-acetylmethionine at position 1.
  • Cellular localizationCytoplasm. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

    • Target information above from: UniProt accession P31946 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    14-3-3 beta protein (Human) images

    • SDS-PAGE - 14-3-3 beta protein (Human) (ab78683)
      SDS-PAGE - 14-3-3 beta protein (Human) (ab78683)
      15% SDS-PAGE showing ab78683 at approximately 28kDa (3µg).

    References for 14-3-3 beta protein (Human) (ab78683)

    ab78683 has not yet been referenced specifically in any publications.

    Publishing research using ab78683 ? Please let us know so that we can cite the reference in this datasheet

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