• Product nameAnti-14-3-3 beta + zeta antibody
    See all 14-3-3 beta + zeta primary antibodies
  • Description
    Rabbit polyclonal to 14-3-3 beta + zeta
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Mouse, Human
    Predicted to work with: Rat
  • Immunogen

    Synthetic non-phosphopeptide derived from human 14-3-3 beta + zeta around the phosphorylation site of serine 184/186 (L-N-SP-P-E).

  • Positive control
    • Extract from 3T3 cells.



Our Abpromise guarantee covers the use of ab79194 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 28 kDa.
ELISA 1/10000.


  • Relevance14-3-3 proteins are highly conserved proteins which play a role in both signal transduction and progression through the cell cycle by binding to and regulating several different proteins. 14-3-3 proteins activate tyrosine and tryptophan hydroxylases and protein kinase C. They mediate signal transduction by binding to phosphoserine-containing proteins. There are at least 7 mammalian isoforms: alpha, beta, gamma, delta, epsilon, zeta, and eta. An eighth subtype, termed theta has been found in rat brain. The 14-3-3 proteins exists in vitro and in vivo as either homo- or heterodimers which interact via their N-terminal domains and are subject to phosphorylation by protein kinase C. 14-3-3 proteins are localized in the cytoplasm of neurons in the cerebral cortex and are axonally transported to the nerve terminals. They may be present at lower levels in various other eukaryotic tissues. Northern blot analysis has shown expression of the eta chain in cultured cell lines derived from various tumors.
  • Cellular localizationCytoplasmic. Melanosome (fractions from stage I to stage IV)
  • Database links
  • Alternative names
    • 14 3 3 protein beta antibody
    • 14 3 3 protein beta/alpha antibody
    • 14 3 3 protein zeta/delta antibody
    • 14 3 3 zeta antibody
    • HS1 antibody
    • KCIP1 antibody
    • YWHAB antibody
    • YWHAZ antibody
    see all

Anti-14-3-3 beta + zeta antibody images

  • All lanes : Anti-14-3-3 beta + zeta antibody (ab79194) at 1/500 dilution

    Lane 1 : Extracts from 3T3 cells
    Lane 2 : Extracts from 3T3 cells with immunising peptide

    Predicted band size : 28 kDa
    Observed band size : 25 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 38 kDa. We are unsure as to the identity of these extra bands.

References for Anti-14-3-3 beta + zeta antibody (ab79194)

ab79194 has not yet been referenced specifically in any publications.

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