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Western blot - 14-3-3 eta antibody (ab58073)
Western blot - 14-3-3 eta antibody (ab58073)
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Product Name 

14-3-3 eta antibody

 

See all 14-3-3 eta antibodies (4)...

Product type 

Primary antibodies

Description 

Mouse monoclonal to 14-3-3 eta

Immunogen 

Recombinant fragment: MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP , corresponding to amino acids 71-170 of Human 14-3-3 eta
BLAST 'MADGNEKKLE KVKAYREKIE KELETVCNDV LSLLDKFLIK NCNDFQYESK VFYLKMKGDY YRYLAEVASG EKKNSVVEAS EAAYKEAFEI SKEQMQPTHP ' with BLAST the sequence with ExPASy or BLAST the sequence with NCBI

Reacts with 
(species key)

Hu

Tested applications 
(see key)

WB


Abreviews 

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Application notes 
(see key)

Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.

This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Cellular localization 

Cytoplasmic

Research areas 

Stem Cells >> Signaling Pathways >> Wnt >> 14-3-3
Signal Transduction >> Adapters >> Cytoplasmic

Relevance 

14-3-3 eta (YWHAH) belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine or phosphothreonine-containing proteins. YWHAH is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. It binds to a large number of partners and binding generally results in the modulation of the activity of the binding partner. The YWHAH gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.

 

Alternative names 14-3-3 eta antibody (ab58073)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

7533    (Human)

GeneCard

    

GC22P030665    (Human)

Omim

    

113508    (Human)

SwissProt

    

Q04917    (Human)

Raised in 

Mouse

Clonality 

Monoclonal

Isotype 

IgG2a

Light chain type 

kappa

Purity 

Protein G purified

Storage buffer 

Preservative: None
PBS, pH 7.2

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this 14-3-3 eta antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

14-3-3 eta antibody images:

Product image  Western blot - 14-3-3 eta antibody (ab58073)

Western blot - 14-3-3 eta antibody (ab58073)

Western blot against tagged recombinant protein immunogen using ab58073 14-3-3 eta antibody at 1ug/ml. Predicted band size of immunogen is 34 kDa

 
 

Search PubMed (MEDLINE) for references to 14-3-3 eta

 

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