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Product Name 

14-3-3 eta antibody

 

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Product type 

Primary antibodies

Description 

Rabbit polyclonal to 14-3-3 eta

Immunogen 

Synthetic peptide from the N terminal area of Sheep 14-3-3 eta

Reacts with 
(species key)

Hu, Ms, Rat, Chk, Cow, Rb, Shp

Tested applications 
(see key)

IHC-Fr, WB


Abreviews 

Customer reviews
(see key)


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Application notes 
(see key)

Recommended dilutions
IHC-Fr: 1/1600 - 1/3200.
WB: 1/3000. Detects a band of approximately 28 kDa (predicted molecular weight: 28 kDa).


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Mouse brain tissue.

Cellular localization 

Cytoplasmic

Research areas 

Stem Cells >> Signaling Pathways >> Wnt >> 14-3-3
Signal Transduction >> Adapters >> Cytoplasmic

Relevance 

14-3-3 eta (YWHAH) belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine or phosphothreonine-containing proteins. YWHAH is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. It binds to a large number of partners and binding generally results in the modulation of the activity of the binding partner. The YWHAH gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat has been associated with early-onset schizophrenia.

 

Alternative names 14-3-3 eta antibody (ab79163)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

416955    (Chicken)
282126    (Cow)
7533    (Human)
22629    (Mouse)
25576    (Rat)

Omim

    

113508    (Human)

SwissProt

    

Q3ZC14    (Cow)
P68509    (Cow)
Q04917    (Human)
P68510    (Mouse)
Q8BJH3    (Mouse)
P68511    (Rat)

Raised in 

Rabbit

Clonality 

Polyclonal

Isotype 

IgG

Purity 

Whole antiserum

Storage buffer 

Preservative: None
Constituents: Whole serum

Form 

Liquid

Concentration 

Concentration not determined - why is this?

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this 14-3-3 eta antibody is on this datasheet. But please do contact us if you would like any reassurance!


 

Search PubMed (MEDLINE) for references to 14-3-3 eta

 

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