2-Furoyl-LIGRLO-amide (2Fly), PAR2 agonist (ab120800)
Key features and details
- Potent and selective PAR2 agonist
- CAS Number: 729589-58-6
- Purity: > 95%
- Soluble in water to 1 mg/ml
- Form / State: Lyophilized
- Source: Synthetic
Overview
-
Product name
2-Furoyl-LIGRLO-amide (2Fly), PAR2 agonist -
Description
Potent and selective PAR2 agonist -
Alternative names
- 2Fly
-
Purity
> 95% -
CAS Number
729589-58-6 -
Chemical structure
Properties
-
Molecular weight
777.96 -
Molecular formula
C36H63N11O8 -
Sequence
LIGRLX (Modifications: N-terminal 2-Furoyl; C-terminal amide; X-6 = Orn) -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 1 mg/ml -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
-
Source
Synthetic
-
Research areas
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
-
SDS download
-
Datasheet download
References (2)
ab120800 has been referenced in 2 publications.
- McMahon DB et al. PAR-2-activated secretion by airway gland serous cells: role for CFTR and inhibition by Pseudomonas aeruginosa. Am J Physiol Lung Cell Mol Physiol 320:L845-L879 (2021). PubMed: 33655758
- Carey RM et al. Polarization of protease-activated receptor 2 (PAR-2) signaling is altered during airway epithelial remodeling and deciliation. J Biol Chem 295:6721-6740 (2020). PubMed: 32241907