2'-Deoxyuridine-5'-monophosphate disodium salt (ab146224)

Overview

  • Product name
    2'-Deoxyuridine-5'-monophosphate disodium salt
  • Description
    Reference substrate for dUMP analogs.
  • Alternative names
    • 2'-Deoxy-5'-uridylic acid disodium salt
    • 2'-dUMP·2Na
    • dUMP disodium salt
  • Biological description

    Used by the enzyme thymidylate synthetase (TS) (EC 2.1.1.45) for the de novo production of dTMP. Reference substrate in studies of dUMP analogs in potential chemotherapy applications.

  • Purity
    > 98%

Properties

  • Molecular weight
    352.10
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C9H11N2Na2O8P
  • CAS Number
    42155-08-8
  • Storage instructions
    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview
    Soluble in water to 10 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:
  • Koehn EM  et al. An unusual mechanism of thymidylate biosynthesis in organisms containing the thyX gene. Nature 458:919-23 (2009). Read more (PubMed: 19370033) »

See 0 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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