20-Hydroxyecdysone (Ecdysterone), Steroid invertebrate hormone (ab142425)
Key features and details
- Steroid invertebrate hormone. Antioxidant and apoptotic agent.
- CAS Number: 5289-74-7
- Purity: > 98%
- Soluble in water to 10 mM, in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
20-Hydroxyecdysone (Ecdysterone), Steroid invertebrate hormone -
Description
Steroid invertebrate hormone. Antioxidant and apoptotic agent. -
Alternative names
- Ecdysterone
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Biological description
Steroid invertebrate hormone. Regulates molting, metamorphosis and reproduction in arthropods. Neuroprotective against oxidative stress in mammals. Inhibits NF-κB activation and iNOS expression. Antioxidant and apoptotic agent.
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Purity
> 98% -
CAS Number
5289-74-7 -
Chemical structure
Properties
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Chemical name
(2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholest-7-en-6-one -
Molecular weight
480.64 -
Molecular formula
C27H44O7 -
PubChem identifier
5459840 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 10 mM, in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
C[C@]12CC[C@H]3C(=CC(=O)[C@H]4[C@@]3(C[C@@H]([C@@H](C4)O)O)C)[C@@]1(CC[C@@H]2[C@](C)([C@@H](CCC(C)(C)O)O)O)O -
Source
Synthetic
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Research areas
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (3)
ab142425 has been referenced in 3 publications.
- Chafino S et al. Activation of EGFR signaling by Tc-Vein and Tc-Spitz regulates the metamorphic transition in the red flour beetle Tribolium castaneum. Sci Rep 11:18807 (2021). PubMed: 34552169
- Edwards-Jorquera SS et al. Trpml controls actomyosin contractility and couples migration to phagocytosis in fly macrophages. J Cell Biol 219:N/A (2020). PubMed: 31940424
- Edwards SS et al. An in vitro method for studying subcellular rearrangements during cell polarization in Drosophila melanogaster hemocytes. Mech Dev 154:277-286 (2018). PubMed: 30096416