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Homogenized hypothalmi recovered from Fischer 344 rats.
In Alzheimer's disease, Ab 24570 provides a strong reaction with extraneuronal (ghost) neurofibrillary tangles. Intraneuronal tangles remain unreactive. Ab 24570 may react with an unusual and sparsely distributed form of phosphorylated neurofilaments that may be exacerbated in certain pathologic conditions. Ab 24570 distinguishes sporadic inclusion-body myositis from hereditary inclusion-body myopathies.
Our Abpromise guarantee covers the use of ab24570 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Predicted molecular weight: 160-200 kDa.|
|IHC-P||Use at an assay dependent dilution.|
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"