Overview

  • Product name
    3R12Rα-Pompilidotoxin
  • Description
    Voltage gated Na+ channel activator
  • Biological description
    Voltage gated Na+ channel activator. Slows TTX-sensitive channel inactivation without changing peak current-voltage relationship or the activation time course. Mutated form of α-Pompilidotoxin. 1Kβ-Pompilidotoxin (ab141836), 1Kα-Pompilidotoxin (ab146032) and 3R12Rα-Pompilidotoxin (ab146034) analog.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Schiavon E  et al. Voltage-gated sodium channel isoform-specific effects of pompilidotoxins. FEBS J 277:918-30 (2010). Read more (PubMed: 20059541) »
  • Konno K  et al. Molecular determinants of binding of a wasp toxin (PMTXs) and its analogs in the Na+ channels proteins. Neurosci Lett 285:29-32 (2000). Read more (PubMed: 10788700) »
  • Sahara Y  et al. A new class of neurotoxin from wasp venom slows inactivation of sodium current. Eur J Neurosci 12:1961-70 (2000). Read more (PubMed: 10886337) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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