Reverse transcriptase inhibitor. Active Lamivudine (ab143062) metabolite. Dideoxynucleoside analog. Shows antiviral effects in vivo. Orally active.
Store at -20°C (desiccating conditions).
Supplied in water (10 mM)
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Dai L et al. Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition. BMC Biochem12:18 (2011).
Read more (PubMed: 21545744) »
Operario DJ et al. Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. Virology335:106-21 (2005).
Read more (PubMed: 15823610) »
Feng JY & Anderson KS Mechanistic studies comparing the incorporation of (+) and (-) isomers of 3TCTP by HIV-1 reverse transcriptase. Biochemistry38:55-63 (1999).
Read more (PubMed: 9890882) »