3TCTP (Lamivudine-5'-triphosphate) (aqueous solution) (ab146755)

Overview

  • Product name
    3TCTP (Lamivudine-5'-triphosphate) (aqueous solution)
  • Description
    Reverse transcriptase inhibitor
  • Biological description
    Reverse transcriptase inhibitor. Active Lamivudine (ab143062) metabolite. Dideoxynucleoside analog. Shows antiviral effects in vivo. Orally active.
  • Purity
    > 95%

Properties

  • Molecular weight
    469.19
  • Chemical structure
    Chemical Structure
  • Molecular formula
    C8H14N3O12P3S
  • CAS Number
    143188-53-8
  • Storage instructions
    Store at -20°C (desiccating conditions).
  • Solubility overview
    Supplied in water (10 mM)
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:
  • Dai L  et al. Effect of reverse transcriptase inhibitors on LINE-1 and Ty1 reverse transcriptase activities and on LINE-1 retrotransposition. BMC Biochem 12:18 (2011). Read more (PubMed: 21545744) »
  • Operario DJ  et al. Comparison of DNA polymerase activities between recombinant feline immunodeficiency and leukemia virus reverse transcriptases. Virology 335:106-21 (2005). Read more (PubMed: 15823610) »
  • Feng JY & Anderson KS Mechanistic studies comparing the incorporation of (+) and (-) isomers of 3TCTP by HIV-1 reverse transcriptase. Biochemistry 38:55-63 (1999). Read more (PubMed: 9890882) »

See 0 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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