Overview

  • Product name4-DAMP
  • Description
    Muscarinic receptor antagonist
  • Biological descriptionMuscarinic antagonist. (Ki values for human receptors are 0.57 (M1), 7.3 (M2), 0.37 (M3), 0.72 (M4) and 0.55 nM (M5)).
  • Purity> 98%

Properties

    References for 4-DAMP (ab120144)

    This product has been referenced in:
    • Ishii M & Kurachi Y Muscarinic acetylcholine receptors. Curr Pharm Des 12:3573-81 (2006). Read more (PubMed: 17073660) »
    • Moriya H  et al. Affinity profiles of various muscarinic antagonists for cloned human muscarinic acetylcholine receptor (mAChR) subtypes and mAChRs in rat heart and submandibular gland. Life Sci 64:2351-8 (1999). Read more (PubMed: 10374898) »
    • Kilbinger H  et al. Comparison of affinities of muscarinic antagonists to pre- and postjunctional receptors in the guinea-pig ileum. Eur J Pharmacol 103:313-20 (1984). Read more (PubMed: 6489444) »

    See all 2 Publications for this product

    Product Wall

    Thank you for contacting us. Below are the results in water.


    1033μL of HPLC grade water were added to 3.1mg of 4-DAMP to achieve a concentration of 3mg/ml and the sealed vial shaken. Some larger solid particles remained undissolved. Read More

    Thank you for contacting Abcam.

    The units of the Ki values are nM.

    We appreciate your bringing this to our attention, thanks to you the datasheet for ab120144 will be updated with the proper units

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"