Overview

  • Product nameAnti-4 Hydroxynonenal antibody
    See all 4 Hydroxynonenal primary antibodies
  • Description
    Goat polyclonal to 4 Hydroxynonenal
  • SpecificityRecognises 4 Hydroxynonenal. Reactive with 4 HNE conjugated BSA. Has minimal cross reactivity with other aldehyde BSA conjugates.
  • Tested applicationsSuitable for: ELISAmore details
  • Species reactivity
    Not applicable
  • Immunogen

    Chemical/ Small Molecule: 4 Hydroxynonenal conjugated Bovine Serum Albumin

Properties

Applications

Our Abpromise guarantee covers the use of ab20953 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/10000.

Target

  • RelevanceAldehydic products of lipid peroxidation, such as 4 hydroxynonenal (4 HNE), have been implicated in the etiology of pathological changes under oxidative stress as a key mediator of oxidative stress induced cell death. It is a stable product of lipid peroxidation, is proarrhythmic and may contribute to the cytotoxic effects of oxidative stress.
  • Cellular localizationCytoplasmic
  • Alternative names
    • 4 HNE antibody
    • 4-Hydroxy-2-Nonenal antibody

References for Anti-4 Hydroxynonenal antibody (ab20953)

This product has been referenced in:
  • Suzuki H  et al. Arachidonate 12/15-lipoxygenase-induced inflammation and oxidative stress are involved in the development of diabetic cardiomyopathy. Diabetes 64:618-30 (2015). Mouse . Read more (PubMed: 25187369) »

See 1 Publication for this product

Product Wall

Thank you for contacting Abcam. The antibody ab20953, anti-4 Hydroxynonenal, has not been tested to work on mouse tissue in western blot. We do not offer sample sizes of our antibodies, but what we can offer is our testing discount program. I ...

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Thank you for your enquiry. Further to correspondence with the originator of this antibody; they recommend that given this antibody has only been applied by ELISA that the synthetic peptide used to raise this antibody is used as a positive control....

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"