Overview

  • Product name
    5'-Iodoresiniferatoxin
  • Description
    Selective TRPV1 antagonist. Some partial agonist activity reported.
  • Biological description
    Highly potent, selective TRPV1 antagonist (IC50 = 0. 7 nM). Some partial agonist activity reported.
  • Purity
    > 98%

Properties

References

This product has been referenced in:
  • Shimizu I  et al. 5-Iodoresiniferatoxin evokes hypothermia in mice and is a partial transient receptor potential vanilloid 1 agonist in vitro. J Pharmacol Exp Ther 314:1378-85 (2005). Read more (PubMed: 15947039) »
  • Seabrook GR  et al. Functional properties of the high-affinity TRPV1 (VR1) vanilloid receptor antagonist (4-hydroxy-5-iodo-3-methoxyphenylacetate ester) iodo-resiniferatoxin. J Pharmacol Exp Ther 303:1052-60 (2002). Read more (PubMed: 12438527) »
  • Wahl P  et al. Iodo-resiniferatoxin, a new potent vanilloid receptor antagonist. Mol Pharmacol 59:9-15 (2001). Read more (PubMed: 11125018) »

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

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