Overview

  • Product name
    Anti-5-oxo-ETE GPCR antibody
    See all 5-oxo-ETE GPCR primary antibodies
  • Description
    Rabbit polyclonal to 5-oxo-ETE GPCR
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Monkey, Gorilla
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to amino acids from the 1st extracellular domain of Human 5-oxo-ETE GPCR.

  • Positive control
    • Human Liver tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab115450 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 11 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins.
  • Tissue specificity
    Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5 oxo ETE acid G protein coupled receptor 1 antibody
    • 5 oxo ETE G protein coupled receptor antibody
    • 5-oxo-ETE G-protein coupled receptor antibody
    • G protein coupled receptor 170 antibody
    • G protein coupled receptor R527 antibody
    • G protein coupled receptor TG1019 antibody
    • G-protein coupled receptor 170 antibody
    • G-protein coupled receptor R527 antibody
    • G-protein coupled receptor TG1019 antibody
    • GPCR antibody
    • GPR170 antibody
    • OTTHUMP00000158809 antibody
    • OXER1 antibody
    • OXER1_HUMAN antibody
    • Oxoeicosanoid (OXE) receptor 1 antibody
    • Oxoeicosanoid receptor 1 antibody
    • TG1019 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue, staining 5-oxo-ETE GPCR with ab115450 at 11 µg/ml.

References

ab115450 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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