5HT1A Receptor peptide (228-240) (ab45743)

Product Name 

5HT1A Receptor peptide (228-240)

Product type 

Proteins and Peptides

Peptide 

Synthetic peptide: C-KTVKKVEKTGADT, corresponding to Internal sequence amino acids 228-240 of Human 5HT1A Receptor.

This peptide was used as an immunogen for ab36135 - 5HT1A Receptor antibody.
BLAST 'C-KTVKKVEKTGADT' with or

Research areas 

Neuroscience >> Endocrine system >> hypothalamic pituitary adrenal axis
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR
Neuroscience >> Neurotransmission >> Receptors / Channels >> GPCR >> Serotonin Receptors

Relevance 

5-HT receptors are receptors for the neurotransmitter and peripheral signal mediator 5-hydroxytryptamine (5-HT), also known as serotonin. 5-HT receptors are of great interest as they also mediate the effects of a broad range of pharmaceutical and hallucinogenic drugs. Like most other members of this family, the 5HT1A receptor (also referred to as 5HT receptor 1A or serotonin receptor 1A) is a G-protein coupled receptor. It acts by decreasing cellular levels of cAMP and causes neuronal inhibition. In mammals, 5HT1A receptor expression is strongest in CNS limbic pathways that control emotion, and 5HT1A receptor function is associated with a number of behavioural effects (sleep, feeding, thermoregulation, aggression and anxiety). Agonists for the 5HT1A receptor include LSD, buspirone, and psilocin.

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

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