Anti-S31 antibody (ab140506)
Key features and details
- Rabbit polyclonal to S31
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-S31 antibody
See all S31 primary antibodies -
Description
Rabbit polyclonal to S31 -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except HTR1F (65%). -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Horse, Chicken, Guinea pig, Cow, Turkey, Chimpanzee, Lizard, Monkey, Zebrafish, Gorilla, Opossum, Orangutan, House sparrow, Bat, Elephant -
Immunogen
Synthetic peptide corresponding to Human S31 (intracellular).
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Positive control
- Human skin and kidney tissues.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab140506 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Relevance
This is one of the several different receptors for 5-HT, a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. The 5-HT1E receptor is expressed in human cortex, caudate, putamen, and amygdala, as well as in dorsal root ganglia and in coronary artery. ESTs have been isolated from human brain cancer libraries. -
Cellular localization
Cell Membrane, Multi-pass membrane protein. -
Database links
- Entrez Gene: 472064 Chimpanzee
- Entrez Gene: 100379275 Guinea pig
- Entrez Gene: 3354 Human
- Omim: 182132 Human
- SwissProt: Q9N2B6 Chimpanzee
- SwissProt: Q6VB83 Guinea pig
- SwissProt: P28566 Human
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Alternative names
- 5 HT1E antibody
- 5 hydroxytryptamine (serotonin) receptor 1E antibody
- 5 hydroxytryptamine (serotonin) receptor 1E G protein coupled antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab140506 has not yet been referenced specifically in any publications.