Overview

  • Product nameAnti-5HT3A receptor antibodySee all 5HT3A receptor primary antibodies ...
  • Description
    Goat polyclonal to 5HT3A receptor
  • Specificityab51950 is expected to recognise both reported isoforms (NP_998786.1 and NP_000860.1).
  • Tested applicationsWB, ICC/IFmore details
  • Species reactivity
    Reacts with: Rat, Human
  • Immunogen

    Synthetic peptide:

    CGPQDFEKSPRDR

    , corresponding to internal sequence amino acids 390-401 of 5HT3A receptor

  • Positive control
    • Human Colon lysates

Properties

Applications

Our Abpromise guarantee covers the use of ab51950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 55 kDa). A band of unknown identity is also consistently observed at 200kDa. This band is successfully blocked by incubation with the immunising peptide but we are unsure of it's identity.
ICC/IF Use at an assay dependent concentration.

Target

  • FunctionThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
  • Tissue specificityExpressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3A sub-subfamily.
  • Cellular localizationCell junction > synapse > postsynaptic cell membrane. Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5 HT 3 antibody
    • 5 HT3 receptor antibody
    • 5 HT3A antibody
    • 5 HT3A receptor antibody
    • 5 HT3R antibody
    • 5 HT3RA antibody
    • 5 hydroxytryptamine (serotonin) receptor 3A antibody
    • 5-HT-3 antibody
    • 5-HT3-A antibody
    • 5-HT3A antibody
    • 5-HT3R antibody
    • 5-hydroxytryptamine receptor 3 antibody
    • 5-hydroxytryptamine receptor 3A antibody
    • 5HT 3 antibody
    • 5HT receptor antibody
    • 5HT3 serotonin receptor antibody
    • 5HT3A_HUMAN antibody
    • 5HT3R antibody
    • HTR3 antibody
    • Htr3a antibody
    • Serotonin gated ion channel receptor antibody
    • Serotonin receptor 3A antibody
    • Serotonin-gated ion channel receptor 3a antibody
    • Serotonin-gated ion channel receptor antibody
    see all

Anti-5HT3A receptor antibody images

  • Anti-5HT3A receptor antibody (ab51950) at 0.3 µg/ml + 35 µg of Human Colon lysate (in RIPA buffer)

    Predicted band size : 55 kDa
    Observed band size : 55 kDa
    Additional bands at : 200 kDa. We are unsure as to the identity of these extra bands.

References for Anti-5HT3A receptor antibody (ab51950)

ab51950 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"