The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000. Predicted molecular weight: 44 kDa.
FunctionThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Post-translational modificationsPhosphorylated. Desensitization of the receptor may be mediated by its phosphorylation. Palmitoylated.