Anti-5HT1F Receptor antibody (ab28695)

Overview

  • Product nameAnti-5HT1F Receptor antibody
    See all 5HT1F Receptor primary antibodies
  • Description
    Rabbit polyclonal to 5HT1F Receptor
  • Specificityab28695 recognises hydroxytryptamine 1F receptor (HTR1F).
  • Tested applicationsSuitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Pig, Chimpanzee
  • Immunogen

    A region within a synthetic peptide: MDFLNSSDQN LTSEELLNRM PSKILVSLTL SGLALMTTTI NSLVIAAIIV, corresponding to N terminal amino acids 1-50 of Human 5HT1F Receptor

  • Positive control
    • Fetal liver lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab28695 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 2.5 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 44 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA 1/62500.

Target

  • Relevance5HT1F is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. 5HT1F is a member of the GPCR family (subfamily: Serotonin). Expression of 5HT1F has been reported in various brain structures, including cortex, hippocampus, trigeminal ganglia, and cerebral blood vessels. Expression in peripheral tissues is limited to uterus, mesentery, and artery. No expression has been detected in heart, kidney, liver, pancreas, or spleen.
  • Cellular localizationCell membrane; Multi pass membrane protein.
  • Database links
  • Alternative names
    • 5 HT 1F antibody
    • 5 HT1F antibody
    • 5 hydroxytryptamine (serotonin) receptor 1F antibody
    • 5 hydroxytryptamine 1F receptor antibody
    • 5 hydroxytryptamine receptor 1E beta antibody
    • 5 hydroxytryptamine receptor 1F antibody
    • 5 hydroxytryptamine serotonin receptor 1E beta antibody
    • 5 hydroxytryptamine serotonin receptor 1F antibody
    • 5HT 1F antibody
    • 5HT1F antibody
    • HGNC5292 antibody
    • HTR 1F antibody
    • HTR1EB antibody
    • HTR1EL antibody
    • HTR1F antibody
    • MR 77 antibody
    • MR77 antibody
    • Serotonin receptor 1E beta antibody
    • Serotonin receptor gene antibody
    see all

Anti-5HT1F Receptor antibody images

References for Anti-5HT1F Receptor antibody (ab28695)

ab28695 has not yet been referenced specifically in any publications.

Product Wall

I am pleased to confirm that the immunogen sequence used to generate ab28695 is 93% homologous to mouse HTR1F. The antibody has therefore good chances of detecting mouse protein, however we cannot guarantee this as it has not been tested. It is ve...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"