Anti-5HT2A Receptor antibody (ab85496)


  • Product nameAnti-5HT2A Receptor antibody
    See all 5HT2A Receptor primary antibodies
  • Description
    Rabbit polyclonal to 5HT2A Receptor
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Pig, Chimpanzee
  • Immunogen

    Synthetic peptide corresponding to a region within N terminal amino acids 2-51 (DILCEENTSL SSTTNSLMQL NDDTRLYSND FNSGEANTSD AFNWTVDSEN) of human 5HT2A Receptor (NP_000612).

  • Positive control
    • 721_B cell lysate



Our Abpromise guarantee covers the use of ab85496 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 53 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.


  • FunctionThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • DomainThe PDZ domain-binding motif is involved in the interaction with INADL, CASK, APBA1, DLG1 and DLG4.
  • Cellular localizationCell membrane. Localizes to the post-synaptic thickening of axo-dendritic synapses.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5 HT 2 antibody
    • 5 HT 2A antibody
    • 5 HT2 receptor antibody
    • 5 HT2A antibody
    • 5 hydroxytryptamine receptor 2A antibody
    • 5-HT-2 antibody
    • 5-HT-2A antibody
    • 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled antibody
    • 5-hydroxytryptamine 2A receptor antibody
    • 5-hydroxytryptamine receptor 2A antibody
    • 5HT2A_HUMAN antibody
    • HTR 2 antibody
    • HTR 2A antibody
    • HTR2 antibody
    • HTR2, formerly antibody
    • HTR2A antibody
    • serotonin 5-HT-2 receptor, formerly antibody
    • serotonin 5-HT-2A receptor antibody
    • Serotonin receptor 2A antibody
    see all

Anti-5HT2A Receptor antibody images

  • Anti-5HT2A Receptor antibody (ab85496) at 1 µg/ml (in 5% skim milk / PBS buffer) + 721_B cell lysate at 10 µg

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 53 kDa
    Observed band size : 53 kDa
    Additional bands at : 65 kDa. We are unsure as to the identity of these extra bands.

References for Anti-5HT2A Receptor antibody (ab85496)

ab85496 has not yet been referenced specifically in any publications.

Product Wall

I can confirm that this antibody already contains a cryoprotectant, sucrose. It will therefore not require any addition of glycerol or other preservative before refreezing.

We do recommend to avoid freeze thaw cycles. If the customer is not ...

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Thanks for your email.

Indeed, with corresponding antibody I meant ab16028.

The anti-5HT2A Receptor ab85496 may or may not detect the peptide ab16195, although to our knowledge this has not been tested yet.

The ab16195 ...

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