• Product name5HT2A Receptor peptide


  • NatureSynthetic


Our Abpromise guarantee covers the use of ab16195 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • FormLiquid
  • Additional notes

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

General Info

  • Alternative names
    • 5 HT 2
    • 5 HT 2A
    • 5 HT2 receptor
    • 5 HT2A
    • 5 hydroxytryptamine receptor 2A
    • 5-HT-2
    • 5-HT-2A
    • 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
    • 5-hydroxytryptamine 2A receptor
    • 5-hydroxytryptamine receptor 2A
    • 5HT2A_HUMAN
    • HTR 2
    • HTR 2A
    • HTR2
    • HTR2, formerly
    • HTR2A
    • serotonin 5-HT-2 receptor, formerly
    • serotonin 5-HT-2A receptor
    • Serotonin receptor 2A
    see all
  • FunctionThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. This receptor is involved in tracheal smooth muscle contraction, bronchoconstriction, and control of aldosterone production.
  • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
  • DomainThe PDZ domain-binding motif is involved in the interaction with INADL, CASK, APBA1, DLG1 and DLG4.
  • Cellular localizationCell membrane. Localizes to the post-synaptic thickening of axo-dendritic synapses.
  • Information by UniProt

References for 5HT2A Receptor peptide (ab16195)

ab16195 has not yet been referenced specifically in any publications.

Product Wall

Thanks for your email.

Indeed, with corresponding antibody I meant ab16028.

The anti-5HT2A Receptor ab85496 may or may not detect the peptide ab16195, although to our knowledge this has not been tested yet.

The ab16195 ...

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Thank you for your enquiry.
Indeed, it would be possible to detect the peptide ab16195 with the corresponding antibody on a Western blot. Given the small size of the peptide I would like torecommendoptimising the protocol conditions to ensure that...

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Thank you for contacting us.

Indeed, the 5HT2A Receptor peptide ab16195 can be used in studies with the anti-5HT2A Receptor antibody ab16028. The peptide is a 20mer and thus has a molecular weight of about 2.2 kDa. As ab16195 is the immunoge...

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Thank you for your inquiry.

No, you shouldn't have to strip the blot. I would wash 3 x 5 min in TBST, but then you should be all set to add the primary.

I hope this information helps. Please contact us with any other que...

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