Application notesIs unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
FunctionThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
DomainThe PDZ domain-binding motif is involved in the interaction with MPDZ.