Anti-5HT2C Receptor antibody [EPR6486] (ab124951)

Overview

  • Product nameAnti-5HT2C Receptor antibody [EPR6486]
    See all 5HT2C Receptor primary antibodies
  • Description
    Rabbit monoclonal [EPR6486] to 5HT2C Receptor
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: Flow Cyt,ICC/IF,IHC-P or IP
  • Species reactivity
    Reacts with: Human
    Does not react with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to residues in Human 5HTR2C Receptor.

  • Positive control
    • SH-SY5Y, A431 and BxPC-3 cell lysates
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Properties

Applications

Our Abpromise guarantee covers the use of ab124951 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 52 kDa.
  • Application notesIs unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.
  • Target

    • FunctionThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
    • Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
    • DomainThe PDZ domain-binding motif is involved in the interaction with MPDZ.
    • Post-translational
      modifications
      N-glycosylated.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • 5 Hydroxytryptamine 2C receptor antibody
      • 5-HT-1C antibody
      • 5-ht-1c receptor antibody
      • 5-HT-2C antibody
      • 5-HT1C antibody
      • 5-HT2C antibody
      • 5-HTR2C antibody
      • 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled antibody
      • 5-hydroxytryptamine receptor 1C antibody
      • 5-hydroxytryptamine receptor 2C antibody
      • 5HT1C antibody
      • 5HT2C antibody
      • 5HT2C_HUMAN antibody
      • 5HTR2C antibody
      • 5Hydroxytryptamine 2C receptor antibody
      • Htr1c antibody
      • HTR2C antibody
      • serotonin 1c receptor antibody
      • serotonin 2c receptor antibody
      • Serotonin 5-HT-2C receptor antibody
      • Serotonin receptor 2C antibody
      see all

    Anti-5HT2C Receptor antibody [EPR6486] images

    • All lanes : Anti-5HT2C Receptor antibody [EPR6486] (ab124951) at 1/1000 dilution

      Lane 1 : SH-SY5Y cell lysate
      Lane 2 : A431 cell lysate
      Lane 3 : BxPC-3 cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      standard HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 52 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References for Anti-5HT2C Receptor antibody [EPR6486] (ab124951)

    ab124951 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"