Overview

  • Product nameAnti-5HT3B receptor antibody
    See all 5HT3B receptor primary antibodies
  • Description
    Goat polyclonal to 5HT3B receptor
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Chimpanzee
  • Immunogen

    Synthetic peptide: C-

    SNYLQTQDQTDQQE

    , corresponding to internal sequence amino acids (near C terminus) 389-402 of Human 5HT3B receptor (NP_006019.1).

  • Positive control
    • Human brain (cerebral cortex, hippocampus and amygdala lysate)

Properties

Applications

Our Abpromise guarantee covers the use of ab90429 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 51 kDa (predicted molecular weight: 50 kDa).

Target

  • FunctionThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.
  • Tissue specificityExpressed in the brain cortex, in the caudate nucleus, the hyppocampus, the thalamus and the amygdala. Detected in the kidney and testis as well as in monocytes of the spleen, small and large intestine, uterus, prostate, ovary and placenta.
  • Sequence similaritiesBelongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3B sub-subfamily.
  • Post-translational
    modifications
    N-glycosylation required for membrane localization.
  • Cellular localizationCell membrane. Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.
  • Information by UniProt
  • Database links
  • Alternative names
    • 5 HT3 B antibody
    • 5 HT3B antibody
    • 5 HTR3B antibody
    • 5 hydroxytryptamine 3 receptor B subunit antibody
    • 5 hydroxytryptamine receptor 3B antibody
    • 5 hydroxytryptamine serotonin receptor 3B antibody
    • 5-HT3-B antibody
    • 5-HT3B antibody
    • 5-hydroxytryptamine receptor 3B antibody
    • 5HT3B_HUMAN antibody
    • 5HTR3B antibody
    • Htr3b antibody
    • Serotonin gated ion channel subunit antibody
    • Serotonin receptor 3B antibody
    see all

Anti-5HT3B receptor antibody images

  • Anti-5HT3B receptor antibody (ab90429) at 1 µg/ml + Human cerebral cortex lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 50 kDa
    Observed band size : ~51 kDa (why is the actual band size different from the predicted?)

References for Anti-5HT3B receptor antibody (ab90429)

ab90429 has not yet been referenced specifically in any publications.

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