Anti-5HT4 Receptor antibody (ab113004)


  • Product nameAnti-5HT4 Receptor antibody
    See all 5HT4 Receptor primary antibodies
  • Description
    Rabbit polyclonal to 5HT4 Receptor
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide conjugated to KLH, corresponding to a region within N terminal amino acids 1-30 of Human 5HT4 Receptor (NP_001035259.1, NP_000861.1, NP_001035262.2, NP_955525.1).

  • Positive control
    • MDA-MB435 cell line and Mouse liver tissue lysates



Our Abpromise guarantee covers the use of ab113004 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/500. Predicted molecular weight: 44 kDa.


  • RelevanceThe 5HT4 Receptor is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulates adenylate cyclase. 5HT4a receptors may play a role in opioid-induced respiratory depression.
  • Cellular localizationCell membrane; Multi-pass membrane protein. Endosome. Note: Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli.
  • Database links
  • Alternative names
    • 5 HT 4 antibody
    • 5 HT4 antibody
    • 5 HT4R antibody
    • 5 hydroxytryptamine (serotonin) receptor 4, G protein coupled antibody
    • 5 hydroxytryptamine 4 receptor antibody
    • 5 hydroxytryptamine receptor 4 antibody
    • 5 hydroxytryptamine serotonin receptor 4 antibody
    • 5 hydroxytryptamine4 receptor antibody
    • 5-HT-4 antibody
    • 5-ht4 antibody
    • 5-HT4R antibody
    • 5H4 antibody
    • 5HT 4 antibody
    • 5HT4 antibody
    • 5ht4 receptor antibody
    • 5HT4R antibody
    • Cardiac 5 HT4 receptor antibody
    • HTR 4 antibody
    • HTR4 antibody
    • serotonin 4 receptor antibody
    • Serotonin 5 HT4 receptor antibody
    • serotonin 5-ht-4 receptor antibody
    • serotonin 5-ht-4a antibody
    • Serotonin receptor 4 antibody
    see all

Anti-5HT4 Receptor antibody images

  • Anti-5HT4 Receptor antibody (ab113004) at 1/100 dilution + MDA-MB435 cell line lysate at 35 µg

    Predicted band size : 44 kDa
  • Anti-5HT4 Receptor antibody (ab113004) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

    Predicted band size : 44 kDa

References for Anti-5HT4 Receptor antibody (ab113004)

ab113004 has not yet been referenced specifically in any publications.

Product Wall

Abcam has not validated the combination of species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (SH-SY5Y)
Permeabilization Yes - Triton X-100 (0,25%)
Specification SH-SY5Y
Blocking step BSA as blocking agent for 30 minute(s) · Concentration: 5% · Temperature: 20°C
Fixative Paraformaldehyde

Abcam user community

Verified customer

Submitted Feb 15 2016

Thank you very much for confirming these details and sending the excellent image! The band at a different molecular weight detected in the liver sample (lane 2) may be due to a tissue-specific post-translational modification pattern: According to th...

Read More

Thank you for taking the time to complete our questionnaire and contact us. I am sorry to hear you have had difficulty obtaining satisfactory results from this 5HT4 antibody. Reviewing this case, I would appreciate if you can confirm some further d...

Read More