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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - 67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free (ab80582)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - 67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free (ab80582)](/ps/datasheet/images/80/ab80582/67kDa-Laminin-Receptor-Primary-antibodies-ab80582-1.jpg)
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Product Name
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67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free
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See all 67kDa Laminin Receptor antibodies (9)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [MLuC5] to 67kDa Laminin Receptor - BSA and Azide free
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Immunogen
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Small cell lung carcinoma N592 live cells.
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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Flow Cyt, ICC/IF, IHC-P, Inhib
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Flow Cyt: Use at an assay dependent dilution.
ICC/IF: Use at an assay dependent dilution.
IHC-P: Use at a concentration of 4 - 8 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
Inhib: Use at an assay dependent dilution. Partially inhibits the binding of soluble laminin.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Breast carcinoma.
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Cellular localization
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Cell Membrane and Cytoplasmic
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Research areas
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Neuroscience >> Cell Adhesion Proteins >> ECM Proteins
Signal Transduction >> Cytoskeleton / ECM >> Basal Lamina
Neuroscience >> Cell Adhesion Proteins >> Cytoskeletal Proteins >> Intermediate Filaments
Neuroscience >> Neurology process >> Neurodegenerative disease >> Prions
Cardiovascular >> Angiogenesis >> Adhesion / ECM >> Extracellular Matrix
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Relevance
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Laminin, one of the major glycoproteins of basement membrane, displays multiple biological activities which are mediated through its interaction with specific cell membrane receptors. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein.
Overexpression of Laminin Receptor is reportedly an independent prognostic factor in breast cancer and correlates with the dissemination of the tumor cells in bone marrow. Laminin Receptors appears to play an important role in tumor invasion and metastasis.
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Alternative names 67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free (ab80582) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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MLuC5
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Isotype
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IgM
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Purity
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Ammonium Sulphate Precipitation
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Storage buffer
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Preservative: None
Constituents: 10mM PBS, pH 7.4
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this 67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for 67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free images, references, products related to ab80582 and other tools.
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67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - 67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free (ab80582)
Formalin-fixed, paraffin-embedded human breast carcinoma stained with ab80582 at 8µg/ml using a peroxidase-conjugate and DAB chromogen. Note cell membrane with some cytoplasmic staining of tumor cells.
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References for 67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free (ab80582)
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This product has been used in: (two most recent references)
Lee JH et al. Vitamin A enhances antitumor effect of a green tea polyphenol on melanoma by upregulating the polyphenol sensing molecule 67-kDa laminin receptor. PLoS One 5:e11051 (2010). Inhib; Mouse. PubMed: 20548792
This clone has been used in:
If you publish research using ab80582 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to 67kDa Laminin Receptor
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67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free - more information
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Protocols for 67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free |
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67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free - related products:
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67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free - other tools:
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Contact Abcam with a Technical Enquiry about 67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - 67kDa Laminin Receptor antibody [MLuC5] - BSA and Azide free (ab80582)](#67kDa-Laminin-Receptor-Primary-antibodies-ab80582-1.jpg)
