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Read our guarantee »Overview
Product name
7-Nitroindazole
Description
NOS inhibitor
Alternative names
- 7-NI
Biological description
Competitive, reversible and non-selective NOS inhibitor. Neuroprotective, anticonvulsant and anxiolytic in vivo.
Purity
> 98%
General notes
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months.
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Properties
Chemical name
7-Nitroindazole
Molecular Weight
163.13
Chemical structure
Molecular formula
C7H5N3O2
CAS Number
2942-42-9
Solubility
Soluble in DMSO to 100 mM and in ethanol to 20 mM
PubChem identifier
0
Storage instructions
Store at -20°C (desiccating conditions).
Research areas
Biochemicals >> Research Area >> Stroke >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Respiratory disease >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Pain & inflammation >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Obesity >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Hypertension >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Heart disease >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Diabetes >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Cancer >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Research Area >> Alzheimer's Disease >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Pharmacology >> Signaling >> Nitric Oxide >> NOS >> Inhibitors
Biochemicals >> Pharmacology >> Enzymes >> Synthetase & synthase >> Inhibitors
Biochemicals >> Chemical Type >> Biochemicals
References for 7-Nitroindazole (ab120233)
This product has been referenced in:
- Moore PK & Handy RL Selective inhibitors of neuronal nitric oxide synthase--is no NOS really good NOS for the nervous system? Trends Pharmacol Sci 18:204-11 (1997).Read more (PubMed: 9226999) »
See 1 publication for this product
Publishing research using ab120233? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"