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Overview

  • Product nameA RAF protein (Active)See all A RAF proteins and peptides ...
  • Protein descriptionRecombinant fragment, corresponding to amino acids 282-606 of Human A RAF, containing the mutations YY301-302DD, with an N-terminal proprietary tag, expressed in a Baculovirus infected Sf9 cell expression system, 63.6 kDa (SwissProt ID P10398).
  • Expression hostBaculovirus infected sf9 cells

    • Properties

  • FormLiquid
  • Storage instructionsAliquot and store at -80°C. Avoid repeated freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Storage bufferPreservative: None
    Constituents: 50% Glycerol, 0.05% Tween 20, 3mM DTT, 25mM Tris HCl, 100mM Sodium chloride, pH 8.0
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab79795 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Functional Studies FuncS: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        A raf 1A Raf proto oncogene serine/threonine protein kinaseARAF
        ARAF 1ARaf proto oncogene serine/threonine protein kinaseARAF_HUMANARAF1Oncogene Araf1Oncogene PKS2PKSPKS 2PKS2Proto oncogene PksProto-oncogene A-RafProto-oncogene A-Raf-1Proto-oncogene PksRAFA 1RAFA1Ras binding protein DA RafSerine/threonine-protein kinase A-Rafv raf murine sarcoma 3611 viral oncogene homologv raf murine sarcoma 3611 viral oncogene homolog 1v raf oncogene homolog 1 (murine sarcoma 3611 virus)
      see all
  • FunctionInvolved in the transduction of mitogenic signals from the cell membrane to the nucleus.
  • Tissue specificityPredominantly in urogenital tissues.
  • Sequence similaritiesBelongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.
    Contains 1 phorbol-ester/DAG-type zinc finger.
    Contains 1 protein kinase domain.
    Contains 1 RBD (Ras-binding) domain.

    • Target information above from: UniProt accession P10398 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    A RAF protein (Active) images

    • SDS-PAGE - A RAF protein (Active) (ab79795)
      SDS-PAGE - A RAF protein (Active) (ab79795)
      10% SDS-PAGE showing ab79795 at approximately 63.6kDa (3µg).

    References for A RAF protein (Active) (ab79795)

    ab79795 has not yet been referenced specifically in any publications.

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