Overview

  • Product nameAnti-AADAC antibodySee all AADAC primary antibodies ...
  • Description
    Mouse monoclonal to AADAC
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Recombinant Fragment
    Predicted to work with: Human
  • Immunogen

    Recombinant fragment: QLLDDPDVKI KLKIQSLIYP ALQPLDVDLP SYQENSNFLF LSKSLMVRFW SEYFTTDRSL EKAMLSRQHV PVESSHLFKF INWSSLLPER FIKGHVYNNP , corresponding to amino acids 201-301 of Human AADAC

Properties

Applications

Our Abpromise guarantee covers the use of ab54694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
  • Application notesWB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionArylacetamide deacetylation is an important enzyme activity in the metabolic activation of arylamine substrates to ultimate carcinogens. Displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionaly causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.
    • Tissue specificityMainly expressed in liver, small intestine, colon and adrenal gland.
    • Sequence similaritiesBelongs to the 'GDXG' lipolytic enzyme family.
    • Cellular localizationEndoplasmic reticulum membrane. Microsome membrane.
    • Target information above from: UniProt accession P22760 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
    • Alternative names
      • AAAD_HUMAN antibody
      • Aada antibody
      • Aadac antibody
      • Arylacetamide deacetylase (esterase) antibody
      • Arylacetamide deacetylase antibody
      • CES5A1 antibody
      • DAC antibody
      see all

    Anti-AADAC antibody images

    • Western blot against tagged recombinant protein immunogen using ab54694 AADAC antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

      This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    References for Anti-AADAC antibody (ab54694)

    ab54694 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"