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Anti-AADAC antibody (ab54694)

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Overview

Product name

Anti-AADAC antibody
See all AADAC products (3) ...

Description

Mouse monoclonal to AADAC

Tested applications

WBmore details

Cross reactivity

Reacts with

Recombinant Fragment

Predicted to work with

Human

Immunogen

Recombinant fragment: QLLDDPDVKI KLKIQSLIYP ALQPLDVDLP SYQENSNFLF LSKSLMVRFW SEYFTTDRSL EKAMLSRQHV PVESSHLFKF INWSSLLPER FIKGHVYNNP , corresponding to amino acids 201-301 of Human AADAC

QLLDDPDVKI KLKIQSLIYP ALQPLDVDLP SYQENSNFLF LSKSLMVRFW SEYFTTDRSL EKAMLSRQHV PVESSHLFKF INWSSLLPER FIKGHVYNNP

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Isotype

IgG2b

Light chain type

kappa

Research areas

Signal Transduction >> Metabolism >> Drug metabolism
Signal Transduction >> Metabolism >> Energy Metabolism

  • Western blot - AADAC antibody (ab54694)Western blot - AADAC antibody (ab54694) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab54694 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

WB: Use at a concentration of 1-5 µg/ml.

This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Microsomal arylacetamide deacetylase (AADAC) competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens. AADAC displays major serine hydrolase activity in liver microsomes. Hydrolyzes also flutamide, which is an antiandrogen drug used for the treatment of prostate cancer that occasionally causes severe hepatotoxicity. Displays cellular triglyceride lipase activity in liver. Increases intracellular fatty acids derived from hydrolysis of newly formed triglyceride stores.

Cellular localization

Endoplasmic reticulum membrane; Microsome membrane; Single-pass type II membrane protein.

Alternative names

  • Aada antibody
  • Arylacetamide deacetylase (esterase) antibody
  • Arylacetamide deacetylase antibody
  • CES5A1 antibody
  • DAC antibody
see all

Database links

Anti-AADAC antibody images:

  Western blot - AADAC antibody (ab54694)

Western blot - AADAC antibody (ab54694)

Western blot against tagged recombinant protein immunogen using ab54694 AADAC antibody at 1ug/ml. Predicted band size of immunogen is 37 kDa.

This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

References for Anti-AADAC antibody (ab54694)

ab54694 has not yet been referenced specifically in any publications.

Publishing research using ab54694? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"