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Overview

  • Product nameAADACL1 protein (Tagged)See all AADACL1 proteins and peptides ...
  • Protein descriptionRecombinant full length Human AADACL1 (amino acids 1-408) with N terminal proprietary tag; Predicted MW 70.62 kDa (inclusive of tag).
  • Uniprot accessionQ6PIU2
  • Molecular weight70.620kDa inclusive of tags
  • Protein length408 amino acids
  • Expression hostWheat germ

    • Properties

  • E.C. Number3.1.1.-
  • FormLiquid
  • Storage instructionsShipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • Storage bufferpH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl
  • Concentration information loading...
  • Additional notesProtein concentration is above or equal to 0.05 µg/µl.
  • Sequence notesMRSSCVLLTALVALAAYYVYIPLPGSVSDPWKLMLLDATF RGAQQVSNLIHYLGLSHHLLALNFIIVSFGKKSAWSSAKV KVTDTDFDGVEVRVFEGPPKPEEPLKRSVVYIHGGGWALA SAKIRYYDELCTAMAEELNAVIVSIEYRLVPKVYFPEQIH DVVRATKYFLKPEVLQKYMVDPGRICISGDSAGGNLAAAL GQQFTQDASLKNKLKLQALIYPVLQALDFNTPSYQQNVNT PILPRYVMVKYWVDYFKGNYDFVQAMIVNNHTSLDVEEAA AVRARLNWTSLLPASFTKNYKPVVQTTGNARIVQELPQLL DARSAPLIADQAVLQLLPKTYIMTCEHDVLRDDGIMYAKR LESAGVEVTLDHFEDGFHGCMIFTSWPTNFSVGIRTRNSY IKWLDQNL
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab132863 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB WB: Use at an assay dependent concentration.
    SDS-PAGE SDS-PAGE: Use at an assay dependent concentration.
    ELISA ELISA: Use at an assay dependent concentration.

    Protein info

    • Alternative names
        Arylacetamide deacetylase like 1Arylacetamide deacetylase-like 1NCEH
        Nceh1NCEH1_HUMANNeutral cholesterol ester hydrolaseNeutral cholesterol ester hydrolase 1
      see all
  • FunctionHydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages, thereby contributing to the development of atherosclerosis. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.
  • Tissue specificityExpressed in monocyte-derived macrophages. Up-regulated in invasive melanoma and breast carcinoma cell lines.
  • Sequence similaritiesBelongs to the 'GDXG' lipolytic enzyme family.
  • Post-translational
    modifications    N-glycosylated.
  • Cellular localizationMembrane. Microsome.

    • Target information above from: UniProt accession Q6PIU2 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    AADACL1 protein (Tagged) images

    • SDS-PAGE - AADACL1 protein (Tagged) (ab132863)
      SDS-PAGE - AADACL1 protein (Tagged) (ab132863)
      12.5% SDS-PAGE analysis of ab132863 stained with Coomassie Blue.

    References for AADACL1 protein (Tagged) (ab132863)

    ab132863 has not yet been referenced specifically in any publications.

    Publishing research using ab132863 ? Please let us know so that we can cite the reference in this datasheet

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