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Overview

  • Product nameAASDHPPT protein
  • Protein descriptionRecombinant fragment of Human AASDHPPT (amino acids 14-309) with an N terminal His tag; 316aa, 36.4kDa. (UniProt ID = Q9NRN7).
  • Uniprot accessionQ9NRN7
  • Molecular weight36.400kDa inclusive of tags
  • Protein length296 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesab99433 is purified using conventional chromatography techniques.
  • Mass spectrometryMALDI-TOF
  • E.C. Number2.7.8.-
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
  • Concentration information loading...
  • SequenceMGSSHHHHHHSSGLVPRGSHMEGVRWAFSCGTWLPSRAEW LLAVRSIQPEEKERIGQFVFARDAKAAMAGRLMIRKLVAE KLNIPWNHIRLQRTAKGKPVLAKDSSNPYPNFNFNISHQG DYAVLAAEPELQVGIDIMKTSFPGRGSIPEFFHIMKRKFT NKEWETIRSFKDEWTQLDMFYRNWALKESFIKAIGVGLGF ELQRLEFDLSPLNLDIGQVYKETRLFLDGEEEKEWAFEES KIDEHHFVAVALRKPDGSRHQDVPSQDDSKPTQRQFTILN FNDLMSSAVPMTPEDPSFWDCFCFTEEIPIRNGTKS
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab99433 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
    MS MS: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        4' phosphopantetheinyl transferase4'-phosphopantetheinyl transferaseAASD PPT
        AASD-PPTAASDHPPTADPPT_HUMANAlpha aminoadipic semialdehyde dehydrogenase phosphopantetheinyl transferaseAlpha-aminoadipic semialdehyde dehydrogenase-phosphopantetheinyl transferaseCGI 80HAH PL-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferaseLYS2LYS5LYS5 ortholog
      see all
  • FunctionCatalyzes the post-translational modification of target proteins by phosphopantetheine. Can transfer the 4'-phosphopantetheine moiety from coenzyme A to a serine residue of a broad range of acceptors, such as the acyl carrier domain of FASN.
  • Tissue specificityDetected in heart, skeletal muscle, placenta, testis, brain, pancreas, liver and kidney.
  • Sequence similaritiesBelongs to the P-Pant transferase superfamily. AcpS family.
  • Post-translational
    modifications    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • Cellular localizationCytoplasm.

    • Target information above from: UniProt accession Q9NRN7 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    AASDHPPT protein images

    • SDS-PAGE - AASDHPPT protein (ab99433)
      SDS-PAGE - AASDHPPT protein (ab99433)
      15% SDS-PAGE showing ab99433 at approximately 36.4kDa (3µg).

    References for AASDHPPT protein (ab99433)

    ab99433 has not yet been referenced specifically in any publications.

    Publishing research using ab99433 ? Please let us know so that we can cite the reference in this datasheet

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