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Anti-ABAT antibody (ab72765)

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Overview

Product name

Anti-ABAT antibody
See all ABAT products (4) ...

Description

Mouse polyclonal to ABAT

Tested applications

WBmore details

Cross reactivity

Reacts with

Human

Immunogen

Full length human ABAT protein (NP_000654.2)

Positive control

Human liver lysate; lysate from ABAT transfected 293T cells.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: PBS, pH 7.2

Concentration

Concentration information loading...

Purity

Protein A purified

Clonality

Polyclonal

Isotype

IgG

  • Western blot - ABAT antibody (ab72765)Western blot - ABAT antibody (ab72765) image (enlarge)

  • Western blot - ABAT antibody (ab72765)Western blot - ABAT antibody (ab72765) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab72765 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Catalyzes the conversion of gamma-aminobutyrate and L-beta-aminoisobutyrate to succinate semialdehyde and methylmalonate semialdehyde, respectively. Can also convert delta-aminovalerate and beta-alanine.

Tissue specificity

Liver > pancreas > brain > kidney > heart > placenta.

Involvement in disease

Defects in ABAT are a cause of gamma-aminobutyrate transaminase deficiency (GABA-AT deficiency) [MIM:613163]. The phenotype of this deficiency includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities.

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.

Cellular localization

Mitochondrion matrix.

Target information above from: UniProt accessionP80404 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • mitochondrial antibody
  • (S) 3 amino 2 methylpropionate transaminase antibody
  • (S)-3-amino-2-methylpropionate transaminase antibody
  • 4 aminobutyrate aminotransferase antibody
  • 4 aminobutyrate aminotransferase, mitochondrial antibody
  • 4-aminobutyrate aminotransferase antibody
  • ABAT antibody
  • FLJ17813 antibody
  • FLJ30272 antibody
  • GABA aminotransferase antibody
  • GABA AT antibody
  • GABA T antibody
  • GABA transaminase antibody
  • GABA transferase antibody
  • GABA-AT antibody
  • GABA-T antibody
  • GABAT antibody
  • GABT_HUMAN antibody
  • Gamma amino N butyrate transaminase antibody
  • Gamma-amino-N-butyrate transaminase antibody
  • hCG1984265 antibody
  • L AIBAT antibody
  • L-AIBAT antibody
  • LAIBAT antibody
  • NPD009 antibody
see all

Anti-ABAT antibody images:

  Western blot - ABAT antibody (ab72765)

Western blot - ABAT antibody (ab72765)

Anti-ABAT antibody (ab72765) at 1/500 dilution + human liver lysate at 25 µg

Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugated at 1/2500 dilution

Predicted band size : 56 kDa

  Western blot - ABAT antibody (ab72765)

Western blot - ABAT antibody (ab72765)

All lanes : Anti-ABAT antibody (ab72765) at 1/500 dilution

Lane 1 : ABAT transfected 293T cell line lysate
Lane 2 : non transfected 293T cell line lysate

Lysates/proteins at 25 µg per lane.

Secondary
Goat Anti-Mouse IgG (H&L)-HRP Conjugated at 1/2500 dilution

Predicted band size : 56 kDa

References for Anti-ABAT antibody (ab72765)

ab72765 has not yet been referenced specifically in any publications.

Publishing research using ab72765? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"