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Western blot - ABCA1 antibody [HJ1] (ab66217)
Western blot - ABCA1 antibody [HJ1] (ab66217)
(enlarge)


Western blot - ABCA1 antibody [HJ1] (ab66217)
Western blot - ABCA1 antibody [HJ1] (ab66217)
(enlarge)


Product Name 

ABCA1 antibody [HJ1]

 

See all ABCA1 antibodies (10)...

Product type 

Primary antibodies

Description 

Mouse monoclonal [HJ1] to ABCA1

Immunogen 

50 kDa N-terminal extracellular loop of ABCA1

Reacts with 
(species key)

Hu, Ms, Rat

Tested applications 
(see key)

WB


Abreviews 

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(see key)


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Application notes 
(see key)

Recommended dilutions
WB: 1/2000. Predicted molecular weight: 254 kDa.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Positive control 
(see definition)

Liver; brain.

Cellular localization 

Cell Membrane

Research areas 

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cardiovascular >> Atherosclerosis >> Lipoprotein metabolism
Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Lipid Metabolism >> Cholesterol Metabolism
Neuroscience >> Cell Type Marker >> Glia marker >> Astrocyte marker

Relevance 

This membrane-associated protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

 

Alternative names ABCA1 antibody [HJ1] (ab66217)

Database links 

The links below go to external sites and will open in a new browser window

Entrez Gene

    

19    (Human)
11303    (Mouse)
313210    (Rat)

Omim

    

600046    (Human)

SwissProt

    

O95477    (Human)
P41233    (Mouse)
Q80ZB2    (Rat)

Unigene

    

719214    (Human)
148916    (Rat)

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

HJ1

Isotype 

IgG

Purity 

Protein G purified

Storage buffer 

Preservative: 0.1% Sodium Azide
Constituents: PBS, Protease inhibitors

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

1.000 mg/ml

Storage instructions 

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

 

At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ABCA1 antibody [HJ1] is on this datasheet. But please do contact us if you would like any reassurance!


See below for ABCA1 antibody [HJ1] images, references, products related to ab66217 and other tools.

 

ABCA1 antibody [HJ1] images:

Product image  Western blot - ABCA1 antibody [HJ1] (ab66217)

Western blot - ABCA1 antibody [HJ1] (ab66217)

All lanes : ABCA1 antibody [HJ1] (ab66217) at 1/2000 dilution

Lane 1 : Human liver lysate
Lane 2 : Human brain lysate
Lane 3 : Rat liver lysate
Lane 4 : Rat brain lysate

Lysates/proteins at 10 µg per lane.


Predicted band size : 254 kDa

 

Product image  Western blot - ABCA1 antibody [HJ1] (ab66217)

Western blot - ABCA1 antibody [HJ1] (ab66217)

All lanes : ABCA1 antibody [HJ1] (ab66217) at 1/2000 dilution

Lane 1 : wild type mouse bain lysate
Lane 2 : ABCA1 overexpressing mouse brain lysate
Lane 3 : ABCA1 (-/-) mouse liver lysate
Lane 4 : wild type mouse liver lysate

Lysates/proteins at 10 µg per lane.


Predicted band size : 254 kDa

 
 

Search PubMed (MEDLINE) for references to ABCA1

 

ABCA1 antibody [HJ1] - more information

Customer reviews (feedback) regarding ABCA1 antibody [HJ1]

Customer FAQs regarding ABCA1 antibody [HJ1]

Protocols for ABCA1 antibody [HJ1]

Price and availability of products related to ABCA1 antibody [HJ1]

 

ABCA1 antibody [HJ1] - related products:

Products for Western blot

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Lysates

 

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ABCA1 antibody [HJ1] - other tools:

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