Overview

  • Product name
  • Description
    Goat polyclonal to ABCA2
  • Host species
    Goat
  • Specificity
    ab179930 is expected to recognize both reported isoforms (NP_001597.2; NP_997698.1).
  • Tested applications
    Suitable for: IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat, Horse, Chicken, Dog, Monkey, Zebrafish, Gorilla
  • Immunogen

    Synthetic peptide corresponding to Human ABCA2 aa 2362-2375 (internal sequence) (Cysteine residue).
    Sequence:

    KKQSDNLEQQETEP


    Database link: Q9BZC7

  • Positive control
    • Human brain cortex tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab179930 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3.75 µg/ml.

Target

  • Function
    Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.
  • Tissue specificity
    Highy expressed in the brain, whereas lower levels of expression is observed in kidney and liver.
  • Sequence similarities
    Belongs to the ABC transporter superfamily. ABCA family.
    Contains 2 ABC transporter domains.
  • Cellular localization
    Endosome. Membrane. Lysosome. Membrane. Forms discrete, punctate intracellular vesicles.
  • Information by UniProt
  • Database links
  • Alternative names
    • ABC2 antibody
    • Abca2 antibody
    • ABCA2_HUMAN antibody
    • ATP binding cassette 2 antibody
    • ATP binding cassette sub family A member 2 antibody
    • ATP binding cassette transporter 2 antibody
    • ATP binding cassette, sub family A (ABC1), member 2 antibody
    • ATP binding cassette, sub family A, member 2 antibody
    • ATP binding cassette, sub family B (MDR/TAP), member 2 antibody
    • ATP-binding cassette 2 antibody
    • ATP-binding cassette sub-family A member 2 antibody
    • ATP-binding cassette transporter 2 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin embedded Human brain cortex tissue labelling ABCA2 with ab179930 at 3.75 µg/ml.

References

ab179930 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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