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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ABCA4 antibody [3F4] (ab77285)
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ABCA4 antibody [3F4] (ab77285)](/ps/datasheet/images/ab77285.gif)
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Product Name
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ABCA4 antibody [3F4]
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See all ABCA4 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [3F4] to ABCA4
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Immunogen
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Partially purified bovine 220 kDa disc rim protein.
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Reacts with
(species key)
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Hu, Ms, Cow, Xl
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Tested applications
(see key)
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IHC-P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
IHC-P: 1/100.
WB: 1/1000. Predicted molecular weight: 257 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Adult mouse retina tissue.
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Cellular localization
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Cell Membrane
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Research areas
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Neuroscience >> Sensory System >> Visual system
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Relevance
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ABCA4 (ATP-binding cassette sub-family A member 4) is a transmembrane protein almost exclusively found in the rims of rod photoreceptor cells in the retina. It is thought to play a role in photoresponse, possibly through the transport of retinoids. ABCA4 is essential for retinal integrity. Defects in the ABCA4 gene are associated with Stargardt disease, which leads to macular degeneration in childhood, and are a common cause of age-related macular degeneration.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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3F4
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Isotype
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IgG
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
Constituents: 50% Glycerol, 100µg/ml BSA, 150mM Sodium chloride, 10mM HEPES, pH 7.5 Material safety datasheet (MSDS) for this product:
Glycerol MSDS
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Purification notes
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ab77285 is protein G purified from culture supernatant.
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Form
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Liquid
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ABCA4 antibody [3F4] is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for ABCA4 antibody [3F4] images, references, products related to ab77285 and other tools.
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ABCA4 antibody [3F4] images:
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 Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ABCA4 antibody [3F4] (ab77285)
ab77285, at a 1/100 dilution, staining ABCA4 in formalin fixed, paraffin embedded adult mouse retina tissue by Immunohistochemisty.
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Search PubMed (MEDLINE) for references to ABCA4
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ABCA4 antibody [3F4] - more information
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Customer reviews (feedback) regarding ABCA4 antibody [3F4] |
Customer FAQs regarding ABCA4 antibody [3F4] |
Protocols for ABCA4 antibody [3F4] |
Price and availability of products related to ABCA4 antibody [3F4] |
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ABCA4 antibody [3F4] - related products:
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ABCA4 antibody [3F4] - other tools:
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Contact Abcam with a Technical Enquiry about ABCA4 antibody [3F4] |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - ABCA4 antibody [3F4] (ab77285)](/index.html?datasheet=77285#ab77285.gif)
