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Overview

  • Product nameABCA5 protein (His-DHFR tag)
  • Protein descriptionRecombinant fragment of Human ABCA5 (amino acids 1464-1642) with an N terminal His-DHFR tag, predicted mwt: 21 kDa without the tag (NM_018672, UniProt ID = Q8WWZ7).
  • Uniprot accessionQ8WWZ7
  • Molecular weight21kDa
  • Protein length179 amino acids
  • Expression hostE. coli

    • Properties

  • Purity= 90 % Purified via His tag
  • FormLyophilised:Reconstitute with 150 µl of water.
  • Storage instructionsShipped at 4°C. Store at -20ºC.
  • Storage bufferConstituents: 0.32% Tris HCl, 0.58% Sodium chloride
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab127783 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        ABC13ABCA5ABCA5_HUMAN
        ATP binding cassette sub family A (ABC1) member 5ATP binding cassette A5ATP binding cassette sub family A member 5ATP-binding cassette sub-family A member 5DKFZp451F117DKFZp779N2435EST90625FLJ16381KIAA1888
      see all
  • FunctionMay play a role in the processing of autolysosomes.
  • Tissue specificityUbiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta.
  • Sequence similaritiesBelongs to the ABC transporter superfamily. ABCA family.
    Contains 2 ABC transporter domains.
  • Developmental stageExpressed in fetal liver, kidney and brain.
  • Post-translational
    modifications    N-glycosylated.
  • Cellular localizationLysosome membrane. Late endosome membrane. Golgi apparatus membrane.

    • Target information above from: UniProt accession Q8WWZ7 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for ABCA5 protein (His-DHFR tag) (ab127783)

    ab127783 has not yet been referenced specifically in any publications.

    Publishing research using ab127783 ? Please let us know so that we can cite the reference in this datasheet

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