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Products:Neuroscience >> Cell Type Marker >> Glia marker >> Astrocyte marker
Overview
Product name
Anti-ABCA7 antibody [4A7-144.1] (Phycoerythrin)
See all ABCA7 products (2) ...
Description
Rat monoclonal [4A7-144.1] to ABCA7 (Phycoerythrin)
Conjugation
Phycoerythrin
Tested applications
Flow Cytmore details
Cross reactivity
Reacts with
Mouse
Immunogen
ABCA7-transfected HeLa cells
Positive control
Mouse spleen cells.
Properties
Form
Liquid
Storage instructions
Store at +4°C in the dark. Do not freeze.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Clone number
4A7-144.1
Isotype
IgG2a
Research areas
Signal Transduction >> Metabolism >> Lipid metabolism
Signal Transduction >> Metabolism >> Plasma Membrane >> ATPases
Cardiovascular >> Lipids / Lipoproteins >> Lipid Metabolism >> Cholesterol Metabolism
Neuroscience >> Cell Type Marker >> Glia marker >> Astrocyte marker
Applications
Show applications key
Our Abpromise guarantee covers the use of ab80047 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Flow Cyt: Use 10µl for 106 cells.
Target
Relevance
ATP-binding cassette (ABC)1 transporters are a superfamily of highly conserved membrane proteins that transport a wide variety of substrates including ions, amino acids, peptides, sugars, lipids, and sterols across cell membranes. ABCA7 is a full-size ABC transporter, the physiological function of which is unclear. This is a protein that shows the highest homology known to ABCA1, an essential molecule for producing of plasma high-density lipoprotein (HDL), and in fact it mimics ABCA1 to mediate the production of HDL from cellular lipid when transfected in vitro. ABCA7 might play a relevant role in regulating lipid metabolism. Mutations of ABC transporters have been identified as the cause of at lease 12 different genetic disorders.
Cellular localization
Cell Membrane and Cytoplasmic
Alternative names
- ABC transporter ABCA7 antibody
- ABC transporter member 7 antibody
- ABCA SSN antibody
see all
Database links
- Entrez Gene: 27403 Mouse
- SwissProt: Q91V24 Mouse
References for Anti-ABCA7 antibody [4A7-144.1] (Phycoerythrin) (ab80047)
ab80047 has not yet been referenced specifically in any publications.
Publishing research using ab80047? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"