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Western blot - ABCB5 antibody (ab87045)
(enlarge)
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Product Name
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ABCB5 antibody
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See all ABCB5 antibodies (3)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to ABCB5
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Immunogen
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Synthetic peptide (Human)
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: 1/1000 - 1/4000. Detects a band of approximately 90 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Lysate from Jurkat, THP or ECL cells
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Cellular localization
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Cell membrane; Multi-pass membrane protein.
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Research areas
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Cancer >> Drug resistance >> P glycoproteins
Signal Transduction >> Metabolism >> Plasma Membrane >> Channels
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Relevance
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ABCB5 is a plasma membrane transporter able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. ABCB5 is also responsible for the resistance to doxorubicin of a subset of malignant melanomas. ABCB5 has more recently been identified as a marker for human malignant-melanoma-initiating cells.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein A purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ABCB5 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for ABCB5 antibody images, references, products related to ab87045 and other tools.
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ABCB5 antibody images:
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 Western blot - ABCB5 antibody (ab87045)
All lanes : ABCB5 antibody (ab87045) at 1/2000 dilution
Lane 1 : Jurkat cell lysate at 45 µg
Lane 2 : THP1 cell lysate at 60 µg
Lane 3 : ECL cell lysate at 60 µg
Predicted band size : 90 kDa
Observed band size : 90 kDa
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Search PubMed (MEDLINE) for references to ABCB5
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ABCB5 antibody - more information
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Customer reviews (feedback) regarding ABCB5 antibody |
Customer FAQs regarding ABCB5 antibody |
Protocols for ABCB5 antibody |
Price and availability of products related to ABCB5 antibody |
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ABCB5 antibody - related products:
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ABCB5 antibody - other tools:
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Contact Abcam with a Technical Enquiry about ABCB5 antibody |
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