Anti-ABCB6 antibody - C-terminal (ab194409)

Overview

  • Product name
    Anti-ABCB6 antibody - C-terminal
    See all ABCB6 primary antibodies
  • Description
    Mouse polyclonal to ABCB6 - C-terminal
  • Host species
    Mouse
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment (GST-tag) corresponding to Human ABCB6 aa 743-842 (C terminal). NP_005680
    Sequence:

    KAPGIILLDEATSALDTSNERAIQASLAKVCANRTTIVVAHRLSTVVNAD QILVIKDGCIVERGRHEALLSRGGVYADMWQLQQGQEETSEDTKPQTMER


    Database link: Q9NP58

  • Positive control
    • HeLa, RAW264.7, PC-12 and NIH3T3 cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab194409 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2500. Predicted molecular weight: 94 kDa.

Target

  • Function
    Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
  • Tissue specificity
    Widely expressed. Highest expression in heart and skeletal muscles.
  • Sequence similarities
    Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
  • Developmental stage
    Highly expressed in fetal liver.
  • Cellular localization
    Mitochondrion outer membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ABC antibody
    • ABC transporter umat antibody
    • ABC14 antibody
    • Abcb6 antibody
    • ABCB6_HUMAN antibody
    • ATP binding cassette sub family B member 6, mitochondrial precursor antibody
    • ATP binding cassette, sub family B (MDR/TAP), member 6 antibody
    • ATP-binding cassette half-transporter antibody
    • ATP-binding cassette sub-family B member 6 antibody
    • ATP-binding cassette sub-family B member 6, mitochondrial antibody
    • DUH3 antibody
    • LAN antibody
    • MCOPCB7 antibody
    • Mitochondrial ABC transporter 3 antibody
    • mitochondrial antibody
    • Mt ABC transporter 3 antibody
    • Mt-ABC transporter 3 antibody
    • MTABC3 antibody
    • P glycoprotein related protein antibody
    • P-glycoprotein-related protein antibody
    • PRP antibody
    • Ubiquitously expressed mammalian ABC half transporter antibody
    • Ubiquitously-expressed mammalian ABC half transporter antibody
    • UMAT antibody
    see all

Images

  • Anti-ABCB6 antibody - C-terminal (ab194409) at 1/500 dilution + NIH3T3 cell lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG at 1/2500 dilution

    Predicted band size: 94 kDa

  • Anti-ABCB6 antibody - C-terminal (ab194409) at 1/500 dilution + RAW264.7 cell lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG at 1/2500 dilution

    Predicted band size: 94 kDa

  • Anti-ABCB6 antibody - C-terminal (ab194409) at 1/500 dilution + PC-12 cell lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG at 1/2500 dilution

    Predicted band size: 94 kDa

  • Anti-ABCB6 antibody - C-terminal (ab194409) at 1/500 dilution + HeLa cell lysate at 50 µg

    Secondary
    Goat Anti-Mouse IgG at 1/2500 dilution

    Predicted band size: 94 kDa

References

ab194409 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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