Anti-ABCB6/PRP antibody (ab47837)
Key features and details
- Rabbit polyclonal to ABCB6/PRP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-ABCB6/PRP antibody
See all ABCB6/PRP primary antibodies -
Description
Rabbit polyclonal to ABCB6/PRP -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to Human ABCB6/PRP aa 440-455 (internal sequence).
Sequence:RAMNTQENATRARAVD
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Positive control
- KB cells transfected with the ABCB6/PRP protein.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.01% Sodium azide
Constituents: 0.42% Potassium phosphate, 0.87% Sodium chloride -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab47837 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Notes |
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IF (microscopy): Use at an assay dependent dilution.
WB: 1/1000 - 1/5000. Predicted molecular weight: 93 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis. -
Tissue specificity
Widely expressed. Highest expression in heart and skeletal muscles. -
Sequence similarities
Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
Contains 1 ABC transmembrane type-1 domain.
Contains 1 ABC transporter domain. -
Developmental stage
Highly expressed in fetal liver. -
Cellular localization
Mitochondrion outer membrane. - Information by UniProt
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Database links
- Entrez Gene: 10058 Human
- Entrez Gene: 74104 Mouse
- Entrez Gene: 140669 Rat
- Omim: 605452 Human
- SwissProt: Q9NP58 Human
- SwissProt: Q9DC29 Mouse
- SwissProt: O70595 Rat
- Unigene: 107911 Human
see all -
Alternative names
- ABC antibody
- ABC transporter umat antibody
- ABC14 antibody
see all
Images
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All lanes : Anti-ABCB6/PRP antibody (ab47837) at 1/1400 dilution
Lane 1 : KB cell lysate expressing Flag™-tagged human ABCB6/PRP protein
Lane 2 : KB cell lysate without a vector insert
Predicted band size: 93 kDa
Observed band size: 104 kDa why is the actual band size different from the predicted?
Additional bands at: 79 kDa (possible truncated form)
Datasheets and documents
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Datasheet download
References (0)
ab47837 has not yet been referenced specifically in any publications.