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Read our guarantee »Products:Cardiovascular >> Hypoxia >> Hypoxia-Regulated
Anti-ABCB6 antibody
Rabbit polyclonal to ABCB6
ICC/IF, ELISA, WBmore details
Reacts with
Human
Predicted to work with
Mouse, Rat
Synthetic peptide: RAMNTQENATRARAVD, corresponding to internal sequence amino acids 440-455 of Human ABCB6
RAMNTQENAT RARAVD
KB cells transfected with the ABCB6 protein.
Liquid
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Sodium Azide
Constituents: 0.15M Sodium chloride, 0.02M Potassium phosphate, pH 7.2
Concentration information loading...
Immunogen affinity purified
Polyclonal
IgG
Cancer >> Drug resistance >> P glycoproteins
Signal Transduction >> Metabolism >> Mitochondrial
Cardiovascular >> Hypoxia >> Hypoxia-Regulated
Western blot - ABCB6 antibody (ab47837)
(enlarge)
Our Abpromise guarantee covers the use of ab47837 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA: 1/40000 - 1/200000.
IF (microscopy): Use at an assay dependent dilution.
WB: 1/1000 - 1/5000. Predicted molecular weight: 93 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
The membrane-associated protein ABCB6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
Mitochondrial outer membrane, multi-pass membrane protein
Western blot - ABCB6 antibody (ab47837)

All lanes : Anti-ABCB6 antibody (ab47837) at 1/1400 dilution
Lane 1 : KB cell lysate expressing Flag™-tagged human ABCB6 protein
Lane 2 : KB cell lysate without a vector insert
Predicted band size : 93 kDa
Observed band size : 104 kDa (why is the actual band size different from the predicted?)
Additional bands at : 79 kDa (possible truncated form).
ab47837 has not yet been referenced specifically in any publications.
Publishing research using ab47837? Please let us know so that we can cite the reference in this datasheet
Concentration of lot no. is
Concentration not available for this lot.
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All lanes : Anti-ABCB6 antibody (ab47837) at 1/1400 dilution
Lane 1 : KB cell lysate expressing Flag™-tagged human ABCB6 protein
Lane 2 : KB cell lysate without a vector insert
Predicted band size : 93 kDa
Observed band size : 104 kDa (why is the actual band size different from the predicted?)
Additional bands at : 79 kDa (possible truncated form).
0
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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