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Western blot - ABCB6 antibody (ab47837)
(enlarge)
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Product Name
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ABCB6 antibody
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to ABCB6
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Immunogen
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Synthetic peptide: RAMNTQENATRARAVD, corresponding to internal sequence amino acids 440-455 of Human ABCB6
BLAST 'RAMNTQENATRARAVD' with  or 
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms, Rat
(Due to sequence homology)
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Tested applications
(see key)
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ELISA, ICC/IF, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: 1/40000 - 1/200000.
IF (microscopy): Use at an assay dependent dilution.
WB: 1/1000 - 1/5000. Predicted molecular weight: 93 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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KB cells transfected with the ABCB6 protein.
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Cellular localization
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Mitochondrial outer membrane, multi-pass membrane protein
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Research areas
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Cancer >> Drug resistance >> P glycoproteins
Signal Transduction >> Metabolism >> Mitochondrial
Cardiovascular >> Hypoxia >> Hypoxia-Regulated
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Relevance
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The membrane-associated protein ABCB6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.01% Sodium Azide
Constituents: 0.15M Sodium chloride, 0.02M Potassium phosphate, pH 7.2 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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1.370 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ABCB6 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for ABCB6 antibody images, references, products related to ab47837 and other tools.
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ABCB6 antibody images:
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 Western blot - ABCB6 antibody (ab47837)
All lanes : ABCB6 antibody (ab47837) at 1/1400 dilution
Lane 1 : KB cell lysate expressing Flag™-tagged human ABCB6 protein
Lane 2 : KB cell lysate without a vector insert
Predicted band size : 93 kDa
Observed band size : 104 kDa (why is the actual band size different from the predicted?)
Additional bands at : 79 kDa (possible truncated form).
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Search PubMed (MEDLINE) for references to ABCB6
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ABCB6 antibody - more information
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Customer reviews (feedback) regarding ABCB6 antibody |
Customer FAQs regarding ABCB6 antibody |
Protocols for ABCB6 antibody |
Price and availability of products related to ABCB6 antibody |
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ABCB6 antibody - related products:
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ABCB6 antibody - other tools:
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Contact Abcam with a Technical Enquiry about ABCB6 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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