Overview
- Product nameAnti-ABCB6 antibody
- DescriptionRabbit polyclonal to ABCB6
- Tested applicationsICC/IF, ELISA, WB more details
- Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat - Immunogen
Synthetic peptide: RAMNTQENATRARAVD, corresponding to internal sequence amino acids 440-455 of Human ABCB6
- Positive controlKB cells transfected with the ABCB6 protein.
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: 0.01% Sodium Azide
Constituents: 0.15M Sodium chloride, 0.02M Potassium phosphate, pH 7.2 -
Concentration information loading... - PurityImmunogen affinity purified
- Clonality Polyclonal
- IsotypeIgG
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Research Areas
Applications
Our Abpromise guarantee covers the use of ab47837 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| ICC/IF | |
| ELISA | |
| WB |
IF (microscopy): Use at an assay dependent dilution.
WB: 1/1000 - 1/5000. Predicted molecular weight: 93 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
- FunctionBinds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
- Tissue specificityWidely expressed. Highest expression in heart and skeletal muscles.
- Sequence similaritiesBelongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
Contains 1 ABC transmembrane type-1 domain.
Contains 1 ABC transporter domain. - Developmental stageHighly expressed in fetal liver.
- Cellular localizationMitochondrion outer membrane.
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Database links
- Entrez Gene: 10058 Human
- Entrez Gene: 74104 Mouse
- Entrez Gene: 140669 Rat
- Omim: 605452 Human
- SwissProt: Q9NP58 Human
- SwissProt: Q9DC29 Mouse
- SwissProt: Q9Z1S2 Rat
- SwissProt: O70595 Rat
- Unigene: 107911 Human
- Unigene: 28663 Mouse
- Unigene: 54408 Rat
see all
Target information above from: UniProt accession
Q9NP58
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010)
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Alternative names
- ABC antibodyABC transporter umat antibodyABC14 antibody
- Abcb6 antibodyABCB6_HUMAN antibodyATP binding cassette sub family B member 6, mitochondrial precursor antibodyATP binding cassette, sub family B (MDR/TAP), member 6 antibodyATP-binding cassette sub-family B member 6 antibodyMitochondrial ABC transporter 3 antibodymitochondrial antibodyMt ABC transporter 3 antibodyMt-ABC transporter 3 antibodyMTABC3 antibodyP glycoprotein related protein antibodyP-glycoprotein-related protein antibodyPRP antibodyUbiquitously expressed mammalian ABC half transporter antibodyUbiquitously-expressed mammalian ABC half transporter antibodyUMAT antibody
see all
Anti-ABCB6 antibody images
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Western blot - ABCB6 antibody (ab47837)All lanes : Anti-ABCB6 antibody (ab47837) at 1/1400 dilution
Lane 1 : KB cell lysate expressing Flag™-tagged human ABCB6 protein
Lane 2 : KB cell lysate without a vector insert
Predicted band size : 93 kDa
Observed band size : 104 kDa (why is the actual band size different from the predicted?)
Additional bands at : 79 kDa (possible truncated form).
References for Anti-ABCB6 antibody (ab47837)
ab47837 has not yet been referenced specifically in any publications.
