Overview

  • Product name
  • Description
    Rabbit polyclonal to ABCB6
  • Tested applications
    Suitable for: ICC/IF, ELISA, WBmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide:

    RAMNTQENATRARAVD

    , corresponding to internal sequence amino acids 440-455 of Human ABCB6

  • Positive control
    • KB cells transfected with the ABCB6 protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab47837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF
ELISA
WB
  • Application notes
    ELISA: 1/40000 - 1/200000.
    IF (microscopy): Use at an assay dependent dilution.
    WB: 1/1000 - 1/5000. Predicted molecular weight: 93 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
    • Tissue specificity
      Widely expressed. Highest expression in heart and skeletal muscles.
    • Sequence similarities
      Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
      Contains 1 ABC transmembrane type-1 domain.
      Contains 1 ABC transporter domain.
    • Developmental stage
      Highly expressed in fetal liver.
    • Cellular localization
      Mitochondrion outer membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • ABC antibody
      • ABC transporter umat antibody
      • ABC14 antibody
      • Abcb6 antibody
      • ABCB6_HUMAN antibody
      • ATP binding cassette sub family B member 6, mitochondrial precursor antibody
      • ATP binding cassette, sub family B (MDR/TAP), member 6 antibody
      • ATP-binding cassette half-transporter antibody
      • ATP-binding cassette sub-family B member 6 antibody
      • ATP-binding cassette sub-family B member 6, mitochondrial antibody
      • DUH3 antibody
      • LAN antibody
      • MCOPCB7 antibody
      • Mitochondrial ABC transporter 3 antibody
      • mitochondrial antibody
      • Mt ABC transporter 3 antibody
      • Mt-ABC transporter 3 antibody
      • MTABC3 antibody
      • P glycoprotein related protein antibody
      • P-glycoprotein-related protein antibody
      • PRP antibody
      • Ubiquitously expressed mammalian ABC half transporter antibody
      • Ubiquitously-expressed mammalian ABC half transporter antibody
      • UMAT antibody
      see all

    Images

    • All lanes : Anti-ABCB6 antibody (ab47837) at 1/1400 dilution

      Lane 1 : KB cell lysate expressing Flag™-tagged human ABCB6 protein
      Lane 2 : KB cell lysate without a vector insert


      Predicted band size : 93 kDa
      Observed band size : 104 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 79 kDa (possible truncated form).

    References

    ab47837 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab47837.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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