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ABCB7 peptide (ab66358)

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Overview

Product name

ABCB7 peptide
See all ABCB7 products (2) ...

Protein description

Synthetic peptide derived from within residues 100 - 200 of Human ABCB7.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab66359 - ABCB7 antibody.

Protein length

752 amino acids

Properties

Purity

70 - 90% by HPLC

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Information available upon request.

Concentration

Concentration information loading...

Research areas

Stem Cells >> Hematopoietic Progenitors >> Myeloid >> Erythrocytic Lineage
Signal Transduction >> Metabolism >> Energy Metabolism

Applications

Application notes

This peptide can be used with studies using ab116606.

Protein info

Function

Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.

Involvement in disease

Defects in ABCB7 are the cause of X-linked sideroblastic anemia with ataxia (ASAT) [MIM:301310]. ASAT is a recessive disorder characterized by an infantile to early childhood onset of nonprogressive cerebellar ataxia and mild anemia with hypochromia and microcytosis.

Sequence similarities

Belongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
Contains 1 ABC transmembrane type-1 domain.
Contains 1 ABC transporter domain.

Cellular localization

Mitochondrion inner membrane.

Target information above from: UniProt accessionO75027 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for ABCB7 peptide (ab66358)

ab66358 has not yet been referenced specifically in any publications.

Publishing research using ab66358? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"