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Overview

  • Product nameABCB7 peptideSee all ABCB7 proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 100 - 200 of Human ABCB7.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab66359 - ABCB7 antibody.
  • Protein length752 amino acids

    • Properties

  • Purity70 - 90% by HPLC
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab116606.

    • Protein info

    • Alternative names
        ABC transporter 7 proteinABC7Abcb7
        ABCB7_HUMANASATAtm1pATP binding cassette 7ATP binding cassette sub family B (MDR/TAP) member 7ATP binding cassette sub family B member 7ATP binding cassette sub family B member 7 mitochondrialATP binding cassette transporter 7ATP-binding cassette sub-family B member 7ATP-binding cassette transporter 7EST140535MDR7mitochondrialMultidrug resistance protein 7P-glycoprotein 7PGP7
      see all
  • FunctionCould be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.
  • Involvement in diseaseDefects in ABCB7 are the cause of X-linked sideroblastic anemia with ataxia (ASAT) [MIM:301310]. ASAT is a recessive disorder characterized by an infantile to early childhood onset of nonprogressive cerebellar ataxia and mild anemia with hypochromia and microcytosis.
  • Sequence similaritiesBelongs to the ABC transporter superfamily. ABCB family. Heavy Metal importer (TC 3.A.1.210) subfamily.
    Contains 1 ABC transmembrane type-1 domain.
    Contains 1 ABC transporter domain.
  • Cellular localizationMitochondrion inner membrane.

    • Target information above from: UniProt accession O75027 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for ABCB7 peptide (ab66358)

    ab66358 has not yet been referenced specifically in any publications.

    Publishing research using ab66358 ? Please let us know so that we can cite the reference in this datasheet

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