Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Signal Transduction >> Metabolism >> Plasma Membrane >> ATPases
Overview
Product name
Anti-ABCB8 antibody
See all ABCB8 products (4) ...
Description
Rabbit polyclonal to ABCB8
Tested applications
ELISA, WBmore details
Cross reactivity
Reacts with
Human
Immunogen
KLH conjugated synthetic peptide selected from the N terminal region of Human ABCB8.
Positive control
HepG2 cell line lysates
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Ammonium Sulphate Precipitation
Purification notes
ab82384 is purified by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Clonality
Polyclonal
Isotype
IgG
Research areas
Signal Transduction >> Metabolism >> Plasma Membrane >> ATPases
-
Western blot - ABCB8 antibody (ab82384)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab82384 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
ELISA: 1/1000ELISA: 1/1000
WB: 1/50 - 1/100.Predicted molecular weight: 80 kDa.
Target
Relevance
ABCB8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCB8 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. ABCB8 may also play a role in the transport of phospholipids into mitochondrial membranes.
Cellular localization
Mitochondrion inner membrane; Multi-pass membrane protein.
Alternative names
- ATP binding cassette sub family B member 8 antibody
- ATP binding cassette sub family B member 8 antibody
- ATP binding cassette sub family B member 8 mitochondrial antibody
see all
Database links
- Entrez Gene: 11194 Human
- Omim: 605464 Human
- SwissProt: Q9NUT2 Human
Anti-ABCB8 antibody images:
Western blot - ABCB8 antibody (ab82384)
Anti-ABCB8 antibody (ab82384) at 1/50 dilution + HepG2 cell line lysates at 35 µg
Predicted band size : 80 kDa
Observed band size : 80 kDa
Additional bands at : 28 kDa,34 kDa,40 kDa. We are unsure as to the identity of these extra bands.
References for Anti-ABCB8 antibody (ab82384)
ab82384 has not yet been referenced specifically in any publications.
Publishing research using ab82384? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"