![Immunocytochemistry - ABCC10 antibody [M7I-3] (ab91451) image](#ABCC10-Primary-antibodies-ab91451-2.jpg)
Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Related products
- Secondary antibodies
Reassurance, Refunds & Replacements
If your product does not perform as described on this datasheet, we will refund or replace your product...
Read our guarantee »Overview
Product name
Anti-ABCC10 antibody [M7I-3]
See all ABCC10 products (3) ...
Description
Rat monoclonal [M7I-3] to ABCC10
Tested applications
Flow Cyt, WB, IHC-Fr, ICCmore details
Cross reactivity
Reacts with
Human
Immunogen
Fusion protein containing internal amino acids 194 - 272 of Human ABCC10.
GPREPWAQEPLLPEDQEPEVAEDGESWLSRFSYAWLAPLL ARGACGELRQPQDICRLPHRLQPTYLARVFQAHWQEGAR
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.1% Sodium Azide
Constituents: 0.7% BSA, Serum free tissue culture supernatant
Purity
Tissue culture supernatant
Clonality
Monoclonal
Clone number
M7I-3
Isotype
IgG
Research areas
Metabolism >> Types of disease >> Cancer
Metabolism >> Pathways and Processes >> Metabolic signaling pathways >> Drug metabolism
Cancer >> Drug resistance >> MRP-related proteins
Signal Transduction >> Metabolism >> Drug metabolism
Signal Transduction >> Metabolism >> Plasma Membrane >> Channels
Signal Transduction >> Metabolism >> Plasma Membrane >> ATPases
-
Immunocytochemistry - ABCC10 antibody [M7I-3] (ab91451)
![Immunocytochemistry - ABCC10 antibody [M7I-3] (ab91451) image](/ps/datasheet/images/91/ab91451/ABCC10-Primary-antibodies-ab91451-2.jpg)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab91451 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Flow Cyt
WB
IHC-Fr
- 1 Image
ICC
Application notes
Flow Cyt: Use at an assay dependent dilution.
ICC (acetone fixed cytospin preparations): 1/20 - 1/50.
IHC-Fr: 1/20.
WB: 1/20 - 1/50. Predicted molecular weight: 162 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion.
Tissue specificity
Isoform 1 is specifically expressed in spleen. Isoform 2 is more widely expressed.
Sequence similarities
Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
Contains 2 ABC transmembrane type-1 domains.
Contains 2 ABC transporter domains.
Cellular localization
Cell membrane.
Target information above from: UniProt accessionQ5T3U5
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- ABCC10 antibody
- ATP binding cassette, sub family C (CFTR/MRP), member 10 antibody
- ATP binding cassette, subfamily C, member 10 antibody
see all
Database links
- Entrez Gene: 89845 Human
- Omim: 612509 Human
- SwissProt: Q5T3U5 Human
- Unigene: 55879 Human
Anti-ABCC10 antibody [M7I-3] images:
Immunocytochemistry - ABCC10 antibody [M7I-3] (ab91451)
ab91451 at 1/20 dilution staining ABCC10 in ABCC10 transfected HEK cells by Immunocytochemistry.
References for Anti-ABCC10 antibody [M7I-3] (ab91451)
This product has been referenced in:
- De Souza R et al. Chemotherapy dosing schedule influences drug resistance development in ovarian cancer. Mol Cancer Ther 10:1289-99 (2011). WB; Mouse.Read more (PubMed: 21551263) »
See 1 publication for this product
Publishing research using ab91451? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"