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Anti-ABCC11 antibody (ab82152)

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Overview

Product name

Anti-ABCC11 antibody
See all ABCC11 products (4) ...

Description

Goat polyclonal to ABCC11

Specificity

This antibody is expected to recognize both reported isoforms (NP_115972.2; NP_660187.1).

Tested applications

WB, ELISAmore details

Cross reactivity

Reacts with

Human

Immunogen

Synthetic peptide: C-KVVEFDRPEVLRK from the internal region (near the C terminus) of the human ABCC11 protein sequence according to NP_115972.2; NP_660187.1.

KVVEFDRPEV LRK

Positive control

Human breast and human testis lysates.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris saline, pH 7.3

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Purification notes

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Clonality

Polyclonal

Isotype

IgG

  • Western blot - ABCC11 antibody (ab82152)Western blot - ABCC11 antibody (ab82152) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab82152 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application notes

Peptide ELISA: Antibody detection limit dilution 1/32,000.
WB: Use at a concentration of 0.5 - 1.5 µg/ml. Predicted molecular weight: 154 kDa.

Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

ABCC11 belongs to the ABC transporter family, conjugate transporter (TC 3.A.1.208) subfamily. It contains two ABC transmembrane type-1 domains and two ABC transporter domains. ABCC11 participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides and enhances the cellular extrusion of cAMP and cGMP. It also stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycocholate and taurocholate, and methotrexate. It probably functions to secrete earwax.

Cellular localization

Membrane; Multi-pass membrane protein.

Alternative names

  • ABCC 11 antibody
  • ATP binding cassette protein C11 antibody
  • ATP binding cassette sub family C (CFTR/MRP) member 11 antibody
  • ATP binding cassette sub family C member 11 antibody
  • ATP binding cassette transporter MRP8 antibody
  • ATP binding cassette transporter sub family C member 11 antibody
  • EWWD antibody
  • MRP8 antibody
  • Multi resistance protein 8 antibody
  • Multidrug resistance associated protein 8 antibody
  • OTTHUMP00000164191 antibody
  • WW antibody
see all

Database links

Anti-ABCC11 antibody images:

  Western blot - ABCC11 antibody (ab82152)

Western blot - ABCC11 antibody (ab82152)

Anti-ABCC11 antibody (ab82152) at 0.5 µg/ml + human breast lysate in RIPA buffer at 35 µg
developed using the ECL technique

Predicted band size : 154 kDa
Observed band size : 125 kDa (why is the actual band size different from the predicted?)


Exposure time : 1 hour

References for Anti-ABCC11 antibody (ab82152)

ab82152 has not yet been referenced specifically in any publications.

Publishing research using ab82152? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"