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Western blot - ABCD1 antibody (ab77364)
(enlarge)
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Product Name
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ABCD1 antibody
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See all ABCD1 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Goat polyclonal to ABCD1
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Immunogen
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Synthetic peptide: EDMQRKGYSEQD, corresponding to amino acids 564-575 of Human ABCD1 (NP_000024.2)
BLAST 'EDMQRKGYSEQD' with  or 
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Reacts with
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Hu
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Predicted to react
(species key)
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Dog, Hrs
(Due to sequence homology)
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Tested applications
(see key)
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ELISA, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/32000.
WB: Use at a concentration of 1 µg/ml. Predicted molecular weight: 83 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Human brain (cerebellum) lysates
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Cellular localization
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Peroxisome membrane; Multi-pass membrane protein.
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Research areas
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Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Signal Transduction >> Metabolism >> Lipid metabolism
Signal Transduction >> Protein Trafficking >> Organelle Proteins
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Peroxisome
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Relevance
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ABCD1 belongs to the ALD subfamily, of the superfamily of ATP-binding cassette (ABC) transporters and is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Goat
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this ABCD1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for ABCD1 antibody images, references, products related to ab77364 and other tools.
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ABCD1 antibody images:
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 Western blot - ABCD1 antibody (ab77364)
All lanes : ABCD1 antibody (ab77364) at 1 µg/ml
Lane 1 : Cell lysate prepared from HEK293 mock transfected cells.
Lane 2 : Cell lysate prepared from HEK293 cells overexpressing human ABCD1.
Predicted band size : 83 kDa
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Search PubMed (MEDLINE) for references to ABCD1
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ABCD1 antibody - more information
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Customer reviews (feedback) regarding ABCD1 antibody |
Customer FAQs regarding ABCD1 antibody |
Protocols for ABCD1 antibody |
Price and availability of products related to ABCD1 antibody |
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ABCD1 antibody - related products:
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ABCD1 antibody - other tools:
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Contact Abcam with a Technical Enquiry about ABCD1 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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