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ABCE1 peptide (ab32269)

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Overview

Product name

ABCE1 peptide

Protein description

Synthetic peptide derived from within residues 550 to the C-terminus of Human ABCE1. (Note: the amino acid sequence is proprietary) This peptide was used as an immunogen for ab32270 - ABCE1 antibody.

Protein length

599 amino acids

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Information available upon request.

Concentration

Concentration information loading...

Research areas

Immunology >> Immune System Diseases >> Antiviral Signaling
Signal Transduction >> Protein Trafficking >> Chaperones >> Other Chaperones
Signal Transduction >> Metabolism >> Plasma Membrane >> ATPases
Signal Transduction >> Adapters >> Transmembrane

Applications

Application notes

This peptide can be used with studies using ab32270.

Protein info

Function

Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.

Sequence similarities

Belongs to the ABC transporter superfamily. ABCE family.
Contains 2 4Fe-4S ferredoxin-type domains.
Contains 2 ABC transporter domains.

Cellular localization

Cytoplasm. Mitochondrion. Localized to clusters of virus formation at the plasma membrane.

Target information above from: UniProt accessionP61221 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

References for ABCE1 peptide (ab32269)

ab32269 has not yet been referenced specifically in any publications.

Publishing research using ab32269? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"