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Overview

  • Product nameABCE1 peptideSee all ABCE1 proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 550 to the C-terminus of Human ABCE1. (Note: the amino acid sequence is proprietary) This peptide was used as an immunogen for ab32270 - ABCE1 antibody.
  • Protein length599 amino acids

    • Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab32270.

    • Protein info

    • Alternative names
        2' 5' oligoadenylate binding protein2''-5''-oligoadenylate-binding protein2'5' oligoadenylate binding protein
        ABC 38ABC 38ABC38ABC38ABCE 1ABCE 1ABCE1ABCE1_HUMANATP binding cassette sub family E (OABP) member 1ATP Binding Cassette Sub Family E Member 1ATP Binding Cassette Sub Family E Member 1ATP-binding cassette sub-family E member 1HuHP 68HuHP68OABPOABPRibonuclease 4 InhibitorRibonuclease 4 InhibitorRibonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitorRibonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitorRibonuclease L inhibitorRLIRLIRNase L InhibitorRNase L InhibitorRNASEL1RNASELIRNS 4IRNS4IRNS4I
      see all
  • FunctionAntagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
  • Sequence similaritiesBelongs to the ABC transporter superfamily. ABCE family.
    Contains 2 4Fe-4S ferredoxin-type domains.
    Contains 2 ABC transporter domains.
  • Cellular localizationCytoplasm. Mitochondrion. Localized to clusters of virus formation at the plasma membrane.

    • Target information above from: UniProt accession P61221 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for ABCE1 peptide (ab32269)

    ab32269 has not yet been referenced specifically in any publications.

    Publishing research using ab32269 ? Please let us know so that we can cite the reference in this datasheet

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