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Overview

  • Product nameABCG5 peptideSee all ABCG5 proteins and peptides ...
  • Protein descriptionSynthetic peptide derived from within residues 150 - 250 of Human ABCG5.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab87116 - ABCG5 antibody.
  • Protein length651 amino acids

    • Properties

  • Purity70 - 90% by HPLC
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferInformation available upon request.
  • Concentration information loading...
  • Research Areas

    • Applications

  • Application notesThis peptide can be used with studies using ab87116.

    • Protein info

    • Alternative names
        ABCG5ABCG5_HUMANATP binding cassette sub family G (WHITE) member 5 (sterolin 1)
        ATP binding cassette sub family G member 5ATP-binding cassette sub-family G member 5Sterolin 1Sterolin-1STSL
      see all
  • FunctionTransporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.
  • Tissue specificityStrongly expressed in the liver, lower levels in the small intestine and colon.
  • Involvement in diseaseDefects in ABCG5 are a cause of sitosterolemia (STSL) [MIM:210250]; also known as phytosterolemia or shellfish sterolemia. It is a rare autosomal recessive disorder characterized by increased intestinal absorption of all sterols including cholesterol, plant and shellfish sterols, and decreased biliary excretion of dietary sterols into bile. Sitosterolemia patients have hypercholesterolemia, very high levels of plant sterols in the plasma, and frequently develop tendon and tuberous xanthomas, accelerated atherosclerosis and premature coronary artery disease.
  • Sequence similaritiesBelongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
    Contains 1 ABC transmembrane type-2 domain.
    Contains 1 ABC transporter domain.
  • Cellular localizationMembrane.

    • Target information above from: UniProt accession Q9H222 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for ABCG5 peptide (ab87830)

    ab87830 has not yet been referenced specifically in any publications.

    Publishing research using ab87830 ? Please let us know so that we can cite the reference in this datasheet

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