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Overview

  • Product nameAnti-ABHD4 antibodySee all ABHD4 primary antibodies ...
  • Description
    Goat polyclonal to ABHD4
  • Tested applicationsELISA, IHC-P more details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Horse, Dog, Pig
  • Immunogen

    Synthetic peptide: RPTNPSEIRAP with a Cysteine residue linker, corresponding to internal sequence amino acids 177-187 of Human ABHD4.

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive controlHuman kidney tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab115473 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
ELISA ELISA: 1/4000.
IHC-P IHC-P: Use a concentration of 3.75 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • FunctionLysophospholipase selective for N-acyl phosphatidylethanolamine (NAPE). Contributes to the biosynthesis of N-acyl ethanolamines, including the endocannabinoid anandamide by hydrolyzing the sn-1 and sn-2 acyl chains from N-acyl phosphatidylethanolamine (NAPE) generating glycerophospho-N-acyl ethanolamine (GP-NAE), an intermediate for N-acyl ethanolamine biosynthesis. Hydrolyzes substrates bearing saturated, monounsaturated, polyunsaturated N-acyl chains. Shows no significant activity towards other lysophospholipids, including lysophosphatidylcholine, lysophosphatidylethanolamine and lysophosphatidylserine.
  • Sequence similaritiesBelongs to the peptidase S33 family. ABHD4/ABHD5 subfamily.

    • Target information above from: UniProt accession Q8TB40 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        ABH4 antibodyAbhd4 antibodyABHD4_HUMAN antibody
        Abhydrolase domain containing 4 antibodyAbhydrolase domain-containing protein 4 antibodyAlpha/beta hydrolase 4 antibodyAlpha/beta-hydrolase 4 antibodyFLJ12816 antibodyLyso N acylphosphatidylethanolamine lipase antibodyLyso-N-acylphosphatidylethanolamine lipase antibody
      see all

    Anti-ABHD4 antibody images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ABHD4 antibody (ab115473)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ABHD4 antibody (ab115473)
      ab115473 at 3.75ug/ml staining ABHD4 in Formalin-fixed, Paraffin-embedded Human kidney tissue by Immunohistochemistry, followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.

    References for Anti-ABHD4 antibody (ab115473)

    ab115473 has not yet been referenced specifically in any publications.

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