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Overview

  • Product nameABP1 protein (His-DHFR tag)See all ABP1 proteins and peptides ...
  • Protein descriptionRecombinant fragment of Human ABP1 (amino acids 45-674) with N terminal His-DHFR tag, predicted mwt: 72 kDa without the tag (UniProt ID = P19801).
  • Uniprot accessionP19801
  • Molecular weight72kDa
  • Protein length630 amino acids
  • Expression hostE. coli

    • Properties

  • Purification notesPurity is 80% by SDS-PAGE.
  • E.C. Number1.4.3.22
  • FormLyophilised:Reconstitute with water to desired concentration.
  • Storage instructionsShipped at 4°C. Store at -20ºC.
  • Storage bufferConstituents: 0.32% Tris HCl, 0.58% Sodium chloride
  • Concentration information loading...
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab127429 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        ABPAbp1ABP1_HUMAN
        Amiloride binding proteinAmiloride binding protein 1Amiloride binding protein 1 (amine oxidase (copper containing))Amiloride sensitive amine oxidaseAmiloride-binding proteinAmiloride-sensitive amine oxidase [copper-containing]AOC1DAODAO1Diamine oxidaseHistaminaseKAOKidney amine oxidase
      see all
  • FunctionCatalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function.
  • Tissue specificityPlacenta and kidney.
  • Sequence similaritiesBelongs to the copper/topaquinone oxidase family.
  • Post-translational
    modifications    Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue.
  • Cellular localizationSecreted > extracellular space.

    • Target information above from: UniProt accession P19801 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for ABP1 protein (His-DHFR tag) (ab127429)

    ab127429 has not yet been referenced specifically in any publications.

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